Affinity Data by PubMed id=19954865

PubMed code 19954865

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50300153 ((2R)-9-amino-2-methyl-2,3-dihydro-1H-cyclopenta[b]...) Show SMILES C[C@H]1Cc2nc3ccccc3c(N)c2C1 \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine \| 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50300154 ((9R)-11-amino-6,6,9-trimethyl-9,10-dihydro-6H-cycl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	288	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50300150 ((3S)-9-amino-3-isopropyl-1,2,3,4-tetrahydroacridin...) Show SMILES CC(C)[C@H]1CCc2c(C1)nc1ccccc1c2N \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	816	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50300155 ((1S,4R)-9-amino-4-tert-butyl-1-methyl-1,2,3,4-tetr...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50300151 ((3R)-9-amino-3-methyl-1,2,3,4-tetrahydroacridine \|...) Show SMILES C[C@@H]1CCc2c(C1)nc1ccccc1c2N \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50300157 ((2R,4R)-9-amino-2,4-methano-3,3-dimethyl-1,2,3,4-t...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50300152 ((2S)-9-Amino-2-isopropyl-2,3-dihydro-1H-cyclopenta...) Show SMILES CC(C)[C@@H]1Cc2nc3ccccc3c(N)c2C1 \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50300158 ((1S,2S,4S)-9-Amino-2,4-methano-1,3,3-trimethyl-1,2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50300156 ((1R,4R)-9-amino-1,4-diisopropyl-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Inhibition of AChE from rat cortex by Ellman assay				Eur J Med Chem 45: 526-35 (2010) Article DOI: 10.1016/j.ejmech.2009.10.039 BindingDB Entry DOI: 10.7270/Q27W6C85
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%