Affinity Data by PubMed id=20004572

PubMed code 20004572

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50029600 (5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305810 (1H-3-(4-sulfamoylphenyl)-4-phenyl-pyrrole-2,5-dion...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305806 (3-(3,4-dihydroxyphenyl)-4-phenyl-1H-pyrrole-2,5-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305808 (3-(4-(methylthio)phenyl)-4-phenyl-1H-pyrrole-2,5-d...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305804 (4-(4-(4-(methylsulfonyl)phenyl)-2,5-dioxo-2,5-dihy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305809 (3-(4-(methylsulfonyl)phenyl)-4-phenyl-1H-pyrrole-2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305807 (3-phenyl-4-(3,4,5-trihydroxyphenyl)-1H-pyrrole-2,5...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305803 (3-(4-(methylthio)phenyl)-4-phenylfuran-2,5-dione \|...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305802 (3-(benzo[d][1,3]dioxol-5-yl)-4-phenylfuran-2,5-dio...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305805 (CHEMBL595852 \| N-(4-(4-(4-(methylthio)phenyl)-2,5-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50305811 (3-(4-hydroxyphenyl)-4-(4-(methylthio)phenyl)-1H-py...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of COX2 assessed as PGF2alpha level by EIA				Bioorg Med Chem Lett 20: 734-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.067 BindingDB Entry DOI: 10.7270/Q2Z31ZQQ
Kyung Hee University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%