Affinity Data by PubMed id=20036560

PubMed code 20036560

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50481610 (CHEMBL609609) Show SMILES F\C(CS)=C/CCCCCNC(=O)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assay				Bioorg Med Chem 18: 605-11 (2010) Article DOI: 10.1016/j.bmc.2009.12.005 BindingDB Entry DOI: 10.7270/Q20C4ZMK
Saga University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50481612 (CHEMBL596660) Show SMILES CN(C)c1ccc(NC(=O)CCCCC\C=C(/F)CS)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assay				Bioorg Med Chem 18: 605-11 (2010) Article DOI: 10.1016/j.bmc.2009.12.005 BindingDB Entry DOI: 10.7270/Q20C4ZMK
Saga University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50481613 (CHEMBL597443) Show SMILES F\C(CS)=C/CCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assay				Bioorg Med Chem 18: 605-11 (2010) Article DOI: 10.1016/j.bmc.2009.12.005 BindingDB Entry DOI: 10.7270/Q20C4ZMK
Saga University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50481611 (CHEMBL599968) Show SMILES F\C(CS)=C/CCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assay				Bioorg Med Chem 18: 605-11 (2010) Article DOI: 10.1016/j.bmc.2009.12.005 BindingDB Entry DOI: 10.7270/Q20C4ZMK
Saga University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assay				Bioorg Med Chem 18: 605-11 (2010) Article DOI: 10.1016/j.bmc.2009.12.005 BindingDB Entry DOI: 10.7270/Q20C4ZMK
Saga University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%