Found 21 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310343
(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)Show SMILES Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2cc[nH]c2c1 Show InChI InChI=1S/C26H21N5O/c27-25-23(19-6-7-22-20(12-19)9-11-29-26(22)32)15-31(30-25)21-3-1-2-17(13-21)18-5-4-16-8-10-28-24(16)14-18/h1-8,10,12-15,28H,9,11H2,(H2,27,30)(H,29,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310342
(6-(1-(3-(1H-benzo[d]imidazol-6-yl)phenyl)-3-amino-...)Show SMILES Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2nc[nH]c2c1 Show InChI InChI=1S/C25H20N6O/c26-24-21(17-4-6-20-18(10-17)8-9-27-25(20)32)13-31(30-24)19-3-1-2-15(11-19)16-5-7-22-23(12-16)29-14-28-22/h1-7,10-14H,8-9H2,(H2,26,30)(H,27,32)(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310352
(7-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-3,...)Show SMILES COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc2CCNC(=O)c2c1 Show InChI InChI=1S/C19H18N4O2/c1-25-15-6-4-14(5-7-15)23-11-17(18(20)22-23)13-3-2-12-8-9-21-19(24)16(12)10-13/h2-7,10-11H,8-9H2,1H3,(H2,20,22)(H,21,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310355
(6-(3-amino-1-(3'-hydroxybiphenyl-3-yl)-1H-pyrazol-...)Show SMILES Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1cccc(O)c1 Show InChI InChI=1S/C24H20N4O2/c25-23-22(17-7-8-21-18(11-17)9-10-26-24(21)30)14-28(27-23)19-5-1-3-15(12-19)16-4-2-6-20(29)13-16/h1-8,11-14,29H,9-10H2,(H2,25,27)(H,26,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310341
(CHEMBL605125 | N-(3'-(3-amino-4-(1-oxo-1,2,3,4-tet...)Show SMILES CS(=O)(=O)Nc1cccc(c1)-c1cccc(c1)-n1cc(c(N)n1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C25H23N5O3S/c1-34(32,33)29-20-6-2-4-16(13-20)17-5-3-7-21(14-17)30-15-23(24(26)28-30)18-8-9-22-19(12-18)10-11-27-25(22)31/h2-9,12-15,29H,10-11H2,1H3,(H2,26,28)(H,27,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310356
(6-(3-amino-1-(3'-methoxybiphenyl-3-yl)-1H-pyrazol-...)Show SMILES COc1cccc(c1)-c1cccc(c1)-n1cc(c(N)n1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C25H22N4O2/c1-31-21-7-3-5-17(14-21)16-4-2-6-20(13-16)29-15-23(24(26)28-29)18-8-9-22-19(12-18)10-11-27-25(22)30/h2-9,12-15H,10-11H2,1H3,(H2,26,28)(H,27,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310345
(6-(3-amino-1-(3-(2-oxoindolin-6-yl)phenyl)-1H-pyra...)Show SMILES Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2CC(=O)Nc2c1 Show InChI InChI=1S/C26H21N5O2/c27-25-22(17-6-7-21-18(10-17)8-9-28-26(21)33)14-31(30-25)20-3-1-2-15(11-20)16-4-5-19-13-24(32)29-23(19)12-16/h1-7,10-12,14H,8-9,13H2,(H2,27,30)(H,28,33)(H,29,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310344
(6-(3-amino-1-(3-(1-methyl-1H-indol-6-yl)phenyl)-1H...)Show SMILES Cn1ccc2ccc(cc12)-c1cccc(c1)-n1cc(c(N)n1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C27H23N5O/c1-31-12-10-17-5-6-19(15-25(17)31)18-3-2-4-22(14-18)32-16-24(26(28)30-32)20-7-8-23-21(13-20)9-11-29-27(23)33/h2-8,10,12-16H,9,11H2,1H3,(H2,28,30)(H,29,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310354
(7-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-3,...)Show SMILES COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc2OCCNC(=O)c2c1 Show InChI InChI=1S/C19H18N4O3/c1-25-14-5-3-13(4-6-14)23-11-16(18(20)22-23)12-2-7-17-15(10-12)19(24)21-8-9-26-17/h2-7,10-11H,8-9H2,1H3,(H2,20,22)(H,21,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM30311
(Pyrrolo-pyrimidone, 4)Show SMILES COc1ccc(cc1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1 Show InChI InChI=1S/C18H14N4O2/c1-24-13-4-2-11(3-5-13)15-8-12(6-7-19-15)16-9-14-17(22-16)20-10-21-18(14)23/h2-10H,1H3,(H2,20,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310353
(8-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-2,...)Show SMILES COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc2CCCNC(=O)c2c1 Show InChI InChI=1S/C20H20N4O2/c1-26-16-8-6-15(7-9-16)24-12-18(19(21)23-24)14-5-4-13-3-2-10-22-20(25)17(13)11-14/h4-9,11-12H,2-3,10H2,1H3,(H2,21,23)(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310347
(4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)Show InChI InChI=1S/C17H16N4O2/c1-23-14-8-6-13(7-9-14)21-10-15(16(18)20-21)11-2-4-12(5-3-11)17(19)22/h2-10H,1H3,(H2,18,20)(H2,19,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310351
(5-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)iso...)Show SMILES COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc2C(=O)NCc2c1 Show InChI InChI=1S/C18H16N4O2/c1-24-14-5-3-13(4-6-14)22-10-16(17(19)21-22)11-2-7-15-12(8-11)9-20-18(15)23/h2-8,10H,9H2,1H3,(H2,19,21)(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50310343
(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)Show SMILES Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2cc[nH]c2c1 Show InChI InChI=1S/C26H21N5O/c27-25-23(19-6-7-22-20(12-19)9-11-29-26(22)32)15-31(30-25)21-3-1-2-17(13-21)18-5-4-16-8-10-28-24(16)14-18/h1-8,10,12-15,28H,9,11H2,(H2,27,30)(H,29,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of p38alpha |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM50310343
(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)Show SMILES Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2cc[nH]c2c1 Show InChI InChI=1S/C26H21N5O/c27-25-23(19-6-7-22-20(12-19)9-11-29-26(22)32)15-31(30-25)21-3-1-2-17(13-21)18-5-4-16-8-10-28-24(16)14-18/h1-8,10,12-15,28H,9,11H2,(H2,27,30)(H,29,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of JNK1 |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM50310343
(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)Show SMILES Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2cc[nH]c2c1 Show InChI InChI=1S/C26H21N5O/c27-25-23(19-6-7-22-20(12-19)9-11-29-26(22)32)15-31(30-25)21-3-1-2-17(13-21)18-5-4-16-8-10-28-24(16)14-18/h1-8,10,12-15,28H,9,11H2,(H2,27,30)(H,29,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of JNK2 |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50310343
(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)Show SMILES Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2cc[nH]c2c1 Show InChI InChI=1S/C26H21N5O/c27-25-23(19-6-7-22-20(12-19)9-11-29-26(22)32)15-31(30-25)21-3-1-2-17(13-21)18-5-4-16-8-10-28-24(16)14-18/h1-8,10,12-15,28H,9,11H2,(H2,27,30)(H,29,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of CDK2 |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310350
(4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)Show SMILES COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H16N4O3S/c1-23-13-6-4-12(5-7-13)20-10-15(16(17)19-20)11-2-8-14(9-3-11)24(18,21)22/h2-10H,1H3,(H2,17,19)(H2,18,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310348
(4-(5-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)Show InChI InChI=1S/C17H16N4O2/c1-23-14-8-6-13(7-9-14)21-16(18)15(10-20-21)11-2-4-12(5-3-11)17(19)22/h2-10H,18H2,1H3,(H2,19,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310346
(4-(1-(4-methoxyphenyl)-1H-pyrazol-4-yl)benzamide |...)Show InChI InChI=1S/C17H15N3O2/c1-22-16-8-6-15(7-9-16)20-11-14(10-19-20)12-2-4-13(5-3-12)17(18)21/h2-11H,1H3,(H2,18,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50310349
(4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)Show InChI InChI=1S/C17H14N4O/c1-22-15-8-6-14(7-9-15)21-11-16(17(19)20-21)13-4-2-12(10-18)3-5-13/h2-9,11H,1H3,(H2,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human MK2 by FRET assay |
Bioorg Med Chem Lett 20: 1293-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5 |
More data for this
Ligand-Target Pair | |
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