Affinity Data by PubMed id=20060304

PubMed code 20060304

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50310362 (3-(2'-Methoxyphenyl)-1H-naphtho[2,1-b]pyran-1-one ...) Show SMILES COc1ccccc1-c1cc(=O)c2c(ccc3ccccc23)o1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50310363 (3-(2'-Pyridinyl)-1H-naphtho[2,1-b]pyran-1-one \| CH...) Show SMILES O=c1cc(oc2ccc3ccccc3c12)-c1ccccn1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50137506 ((B(a)P) \| 3,4-BP \| 3,4-Benzopyrene \| 3,4-Benzpyren...) Show SMILES c1ccc2c(c1)cc1ccc3cccc4ccc2c1c34 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50310359 (3-(2',6'-Dimethylphenyl)-1H-naphtho[2,1-b]pyran-1-...) Show SMILES Cc1cccc(C)c1-c1cc(=O)c2c(ccc3ccccc23)o1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50310361 (3-(2',6'-Difluorophenyl)-1H-naphtho[2,1-b]pyran-1-...) Show SMILES Fc1cccc(F)c1-c1cc(=O)c2c(ccc3ccccc23)o1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50028963 (3-Phenyl-1H-naphtho[2,1-b]pyran-1-one \| 3-Phenyl-b...) Show SMILES O=c1cc(oc2ccc3ccccc3c12)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50310358 (3-(2'-Methylphenyl)-1H-naphtho[2,1-b]pyran-1-one \|...) Show SMILES Cc1ccccc1-c1cc(=O)c2c(ccc3ccccc23)o1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50310360 (3-(2'-Fluorophenyl)-1H-naphtho[2,1-b]pyran-1-one \|...) Show SMILES Fc1ccccc1-c1cc(=O)c2c(ccc3ccccc23)o1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50310357 (CHEMBL599552 \| indigo) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%