Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50011938 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50009001 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50011932 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50011934 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50011930 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50011931 ((2E)‐3‐phenylprop‐2‐enR...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50011935 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50011938 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50011935 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50011934 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50011930 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50011937 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50011933 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50009001 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50011932 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50011934 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50011933 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus) | BDBM50011936 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50011938 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50011930 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50011935 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50011931 ((2E)‐3‐phenylprop‐2‐enR...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50011931 ((2E)‐3‐phenylprop‐2‐enR...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50011933 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50011936 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 3.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50011932 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50011936 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50011937 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50009001 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50011937 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes | J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6 | |||||||||||
More data for this Ligand-Target Pair |