Found 3 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histone deacetylase
(Homo sapiens (Human)) | BDBM50481946
(CHEMBL1077183)Show SMILES O=[#6](-[#6]-[#6]-[#6]-[#6]-[#6][Se;v2]C#N)-[#7]-c1ccccc1 Show InChI InChI=1S/C13H16N2OSe/c14-11-17-10-6-2-5-9-13(16)15-12-7-3-1-4-8-12/h1,3-4,7-8H,2,5-6,9-10H2,(H,15,16) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Pennsylvania State Hershey College of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC in human HeLa cell nuclear extract after 15 mins by colorimetric assay |
Bioorg Med Chem Lett 20: 2044-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.07.068
BindingDB Entry DOI: 10.7270/Q2DF6V2B |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50005711
(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)Show SMILES C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Pennsylvania State Hershey College of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC in human HeLa cell nuclear extract after 15 mins by colorimetric assay |
Bioorg Med Chem Lett 20: 2044-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.07.068
BindingDB Entry DOI: 10.7270/Q2DF6V2B |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Histone deacetylase
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 196 | n/a | n/a | n/a | n/a | n/a | n/a |
Pennsylvania State Hershey College of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC in human HeLa cell nuclear extract after 15 mins by colorimetric assay |
Bioorg Med Chem Lett 20: 2044-7 (2010)
Article DOI: 10.1016/j.bmcl.2009.07.068
BindingDB Entry DOI: 10.7270/Q2DF6V2B |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
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