Found 3 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 2E1
(Homo sapiens (Human)) | BDBM92499
(Omega-imidazolyl dodecanoic acid)Show InChI InChI=1S/C15H26N2O2/c18-15(19)10-8-6-4-2-1-3-5-7-9-12-17-13-11-16-14-17/h11,13-14H,1-10,12H2,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB Article PubMed
| n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
| Assay Description Binding assay using CYP2E1. |
J Biol Chem 285: 22282-90 (2010)
Article DOI: 10.1074/jbc.M110.109017 BindingDB Entry DOI: 10.7270/Q2FF3QZH |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Cytochrome P450 2E1
(Homo sapiens (Human)) | BDBM92498
(Omega-imidazolyl decanoic acid)Show InChI InChI=1S/C13H22N2O2/c16-13(17)8-6-4-2-1-3-5-7-10-15-11-9-14-12-15/h9,11-12H,1-8,10H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
| Assay Description Binding assay using CYP2E1. |
J Biol Chem 285: 22282-90 (2010)
Article DOI: 10.1074/jbc.M110.109017 BindingDB Entry DOI: 10.7270/Q2FF3QZH |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Cytochrome P450 2E1
(Homo sapiens (Human)) | BDBM92497
(CHEMBL542051 | Omega-imidazolyl octanoic acid)Show InChI InChI=1S/C11H18N2O2/c14-11(15)6-4-2-1-3-5-8-13-9-7-12-10-13/h7,9-10H,1-6,8H2,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB Article PubMed
| n/a | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
| Assay Description Binding assay using CYP2E1. |
J Biol Chem 285: 22282-90 (2010)
Article DOI: 10.1074/jbc.M110.109017 BindingDB Entry DOI: 10.7270/Q2FF3QZH |
More data for this Ligand-Target Pair | 3D Structure (crystal) |