Affinity Data by PubMed id=20478710

PubMed code 20478710

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	10.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50143282 ((-)-cytisine \| (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...) Show SMILES O=c1cccc2[C@H]3CNC[C@H](C3)Cn12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321015 (4-Methyl-3-oxa-4,10-diazatricyclo[6.3.1.0'2,6]dode...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321023 ((-)-Norferruginine \| CHEMBL1164304) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321018 (CHEMBL1163516 \| and 5-bromo-3-oxa-4,11-diazatricyc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321020 (5-Methoxy-3-oxa-4,11-diazatricyclo[6.2.1.0'2,6]und...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.82E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321013 (3-bromo-5-oxa-4,10-diazatricyclo[6.3.1.0'2,6]dodec...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.85E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321019 (3-Methoxy-5-oxa-4,11-diazatricyclo[6.2.1.0'2,6]und...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321021 (4-Methyl-5-oxa-4,11-diazatricyclo[6.2.1.0'2,6]unde...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321016 (4-Methyl-5-oxa-4,10-diazatricyclo[6.3.1.0'2,6]dode...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321022 (4-Methyl-3-oxa-4,11-diazatricyclo[6.2.1.0'2,6]unde...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50321017 (3-Bromo-5-oxa-4,11-diazatricyclo[6.2.1.0'2,6]undec...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.09E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50378786 (CHEMBL1794974) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membrane				Bioorg Med Chem 18: 4498-508 (2010) Article DOI: 10.1016/j.bmc.2010.04.065 BindingDB Entry DOI: 10.7270/Q27M08XD
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%