Affinity Data by PubMed id=20491506

PubMed code 20491506

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50322457 (6-((E)-4-(((1-(50-Deoxy-adenosin-50-yl)-1H-1,2,3-t...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH2				J Med Chem 53: 4768-78 (2010) Article DOI: 10.1021/jm100424m BindingDB Entry DOI: 10.7270/Q2RN382B
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50322459 (6-((E)-4-(4-(Adenosin-50-yl)methyl-1H-1,2,3-triazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH2				J Med Chem 53: 4768-78 (2010) Article DOI: 10.1021/jm100424m BindingDB Entry DOI: 10.7270/Q2RN382B
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50322459 (6-((E)-4-(4-(Adenosin-50-yl)methyl-1H-1,2,3-triazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH1				J Med Chem 53: 4768-78 (2010) Article DOI: 10.1021/jm100424m BindingDB Entry DOI: 10.7270/Q2RN382B
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50322457 (6-((E)-4-(((1-(50-Deoxy-adenosin-50-yl)-1H-1,2,3-t...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH1				J Med Chem 53: 4768-78 (2010) Article DOI: 10.1021/jm100424m BindingDB Entry DOI: 10.7270/Q2RN382B
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50322458 (6-(2-(4-(Adenosin-50-yl)methyl-1H-1,2,3-triazol-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH2				J Med Chem 53: 4768-78 (2010) Article DOI: 10.1021/jm100424m BindingDB Entry DOI: 10.7270/Q2RN382B
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50322458 (6-(2-(4-(Adenosin-50-yl)methyl-1H-1,2,3-triazol-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH1				J Med Chem 53: 4768-78 (2010) Article DOI: 10.1021/jm100424m BindingDB Entry DOI: 10.7270/Q2RN382B
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50322456 (6-(2-(((1-(50-Deoxy-adenosin-50-yl)-1H-1,2,3-triaz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH2				J Med Chem 53: 4768-78 (2010) Article DOI: 10.1021/jm100424m BindingDB Entry DOI: 10.7270/Q2RN382B
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50322456 (6-(2-(((1-(50-Deoxy-adenosin-50-yl)-1H-1,2,3-triaz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH1				J Med Chem 53: 4768-78 (2010) Article DOI: 10.1021/jm100424m BindingDB Entry DOI: 10.7270/Q2RN382B
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%