Affinity Data by PubMed id=20576329

PubMed code 20576329

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX1				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX2				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50326126 (((m-tolylimino)methyl)-4H-chromen-4-one \| 3-{[(3-M...) Show SMILES Cc1cccc(c1)\N=C\c1coc2ccccc2c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX2				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50326124 ((E)-2-((4-oxo-4H-chromen-3-yl)methyleneamino)benzo...) Show SMILES OC(=O)c1ccccc1\N=C\c1coc2ccccc2c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX2				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50326127 (4-methyl-N'-((4-oxo-4H-chromen-3-yl)methylene)benz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX1				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50326127 (4-methyl-N'-((4-oxo-4H-chromen-3-yl)methylene)benz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX2				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50326128 (CHEMBL1241822 \| N'-((4-oxo-4H-chromen-3-yl)methyle...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX1				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM22360 (2-(acetyloxy)benzoate \| 2-(acetyloxy)benzoic acid ...) Show SMILES CC(=O)Oc1ccccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX1				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50326128 (CHEMBL1241822 \| N'-((4-oxo-4H-chromen-3-yl)methyle...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX2				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM22360 (2-(acetyloxy)benzoate \| 2-(acetyloxy)benzoic acid ...) Show SMILES CC(=O)Oc1ccccc1C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX2				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50326125 (CHEMBL1240658 \| N'-((4-oxo-4H-chromen-3-yl)methyle...) Show SMILES CCCC(=O)NN=Cc1coc2ccccc2c1=O \|w:7.7\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX2				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50326125 (CHEMBL1240658 \| N'-((4-oxo-4H-chromen-3-yl)methyle...) Show SMILES CCCC(=O)NN=Cc1coc2ccccc2c1=O \|w:7.7\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX1				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50326124 ((E)-2-((4-oxo-4H-chromen-3-yl)methyleneamino)benzo...) Show SMILES OC(=O)c1ccccc1\N=C\c1coc2ccccc2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX1				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50326126 (((m-tolylimino)methyl)-4H-chromen-4-one \| 3-{[(3-M...) Show SMILES Cc1cccc(c1)\N=C\c1coc2ccccc2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of COX1				Eur J Med Chem 45: 4058-64 (2010) Article DOI: 10.1016/j.ejmech.2010.05.065 BindingDB Entry DOI: 10.7270/Q2GQ6ZQG
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%