Affinity Data by PubMed id=20646926

PubMed code 20646926

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50034839 (8-Chloro-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tri...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha1beta2gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50034839 (8-Chloro-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tri...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha3beta2gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50034839 (8-Chloro-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tri...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha2beta2gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
GABA A receptor alpha-4/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034820 (8-Chloro-3-methoxymethyl-5-methyl-4,5-dihydro-2,5,...) Show SMILES COCc1ncn-2c1CN(C)C(=O)c1cc(Cl)ccc-21 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	38.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha4beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034820 (8-Chloro-3-methoxymethyl-5-methyl-4,5-dihydro-2,5,...) Show SMILES COCc1ncn-2c1CN(C)C(=O)c1cc(Cl)ccc-21 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha2beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034820 (8-Chloro-3-methoxymethyl-5-methyl-4,5-dihydro-2,5,...) Show SMILES COCc1ncn-2c1CN(C)C(=O)c1cc(Cl)ccc-21 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha3beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034820 (8-Chloro-3-methoxymethyl-5-methyl-4,5-dihydro-2,5,...) Show SMILES COCc1ncn-2c1CN(C)C(=O)c1cc(Cl)ccc-21 Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha1beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034820 (8-Chloro-3-methoxymethyl-5-methyl-4,5-dihydro-2,5,...) Show SMILES COCc1ncn-2c1CN(C)C(=O)c1cc(Cl)ccc-21 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha5beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
GABA A receptor alpha-4/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034826 (3-Acetyl-8-chloro-5-methyl-4,5-dihydro-2,5,10b-tri...) Show SMILES CN1Cc2c(ncn2-c2ccc(Cl)cc2C1=O)C(C)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha4beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034826 (3-Acetyl-8-chloro-5-methyl-4,5-dihydro-2,5,10b-tri...) Show SMILES CN1Cc2c(ncn2-c2ccc(Cl)cc2C1=O)C(C)=O Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha1beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034826 (3-Acetyl-8-chloro-5-methyl-4,5-dihydro-2,5,10b-tri...) Show SMILES CN1Cc2c(ncn2-c2ccc(Cl)cc2C1=O)C(C)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha3beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034826 (3-Acetyl-8-chloro-5-methyl-4,5-dihydro-2,5,10b-tri...) Show SMILES CN1Cc2c(ncn2-c2ccc(Cl)cc2C1=O)C(C)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.95E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha5beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50034826 (3-Acetyl-8-chloro-5-methyl-4,5-dihydro-2,5,10b-tri...) Show SMILES CN1Cc2c(ncn2-c2ccc(Cl)cc2C1=O)C(C)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.38E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha2beta3gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
University of Massachusetts Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%