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PubMed code 2066991

Compile data set for download or QSAR
Found 40 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012476
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexyl-5,7,8-trimethoxy-...)
Show SMILES CCCCCCc1c(oc2c(OC)c(OC)cc(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C24H28O7/c1-5-6-7-8-9-15-21(27)20-18(28-2)13-19(29-3)23(30-4)24(20)31-22(15)14-10-11-16(25)17(26)12-14/h10-13,25-26H,5-9H2,1-4H3
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n/an/a 58n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012465
PNG
(2-(3,4-Dihydroxy-phenyl)-5,7,8-trimethoxy-3-octyl-...)
Show SMILES CCCCCCCCc1c(oc2c(OC)c(OC)cc(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C26H32O7/c1-5-6-7-8-9-10-11-17-23(29)22-20(30-2)15-21(31-3)25(32-4)26(22)33-24(17)16-12-13-18(27)19(28)14-16/h12-15,27-28H,5-11H2,1-4H3
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n/an/a 62n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012461
PNG
(3-Decyl-2-(3,4-dihydroxy-phenyl)-5,7,8-trimethoxy-...)
Show SMILES CCCCCCCCCCc1c(oc2c(OC)c(OC)cc(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C28H36O7/c1-5-6-7-8-9-10-11-12-13-19-25(31)24-22(32-2)17-23(33-3)27(34-4)28(24)35-26(19)18-14-15-20(29)21(30)16-18/h14-17,29-30H,5-13H2,1-4H3
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n/an/a 86n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012451
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexyloxy-5,7,8-trimetho...)
Show SMILES CCCCCCOc1c(oc2c(OC)c(OC)cc(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C24H28O8/c1-5-6-7-8-11-31-24-20(27)19-17(28-2)13-18(29-3)22(30-4)23(19)32-21(24)14-9-10-15(25)16(26)12-14/h9-10,12-13,25-26H,5-8,11H2,1-4H3
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n/an/a 88n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012473
PNG
(3-Butyl-2-(3,4-dihydroxy-phenyl)-5,7,8-trimethoxy-...)
Show SMILES CCCCc1c(oc2c(OC)c(OC)cc(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C22H24O7/c1-5-6-7-13-19(25)18-16(26-2)11-17(27-3)21(28-4)22(18)29-20(13)12-8-9-14(23)15(24)10-12/h8-11,23-24H,5-7H2,1-4H3
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n/an/a 100n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012475
PNG
(2-(3,4-Dihydroxy-phenyl)-3-dodecyl-5,7,8-trimethox...)
Show SMILES CCCCCCCCCCCCc1c(oc2c(OC)c(OC)cc(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C30H40O7/c1-5-6-7-8-9-10-11-12-13-14-15-21-27(33)26-24(34-2)19-25(35-3)29(36-4)30(26)37-28(21)20-16-17-22(31)23(32)18-20/h16-19,31-32H,5-15H2,1-4H3
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n/an/a 105n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012456
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexyl-5-hydroxy-6,7-dim...)
Show SMILES CCCCCCc1c(O)c2c(cc(OC)c(OC)c2=O)oc1-c1ccc(O)c(O)c1
Show InChI InChI=1S/C23H26O7/c1-4-5-6-7-8-14-20(26)19-17(12-18(28-2)23(29-3)21(19)27)30-22(14)13-9-10-15(24)16(25)11-13/h9-12,24-26H,4-8H2,1-3H3
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n/an/a 110n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012447
PNG
(3-Butyl-2-(3,4-dihydroxy-phenyl)-5-hydroxy-7,8-dim...)
Show SMILES CCCCc1c(oc2c(OC)c(OC)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C21H22O7/c1-4-5-6-12-18(25)17-15(24)10-16(26-2)20(27-3)21(17)28-19(12)11-7-8-13(22)14(23)9-11/h7-10,22-24H,4-6H2,1-3H3
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n/an/a 115n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012450
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexyl-5-hydroxy-7,8-dim...)
Show SMILES CCCCCCc1c(oc2c(OC)c(OC)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C23H26O7/c1-4-5-6-7-8-14-20(27)19-17(26)12-18(28-2)22(29-3)23(19)30-21(14)13-9-10-15(24)16(25)11-13/h9-12,24-26H,4-8H2,1-3H3
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n/an/a 115n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012437
PNG
(2-(3,4-Dihydroxy-phenyl)-5,7,8-trimethoxy-3-tetrad...)
Show SMILES CCCCCCCCCCCCCCc1c(oc2c(OC)c(OC)cc(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C32H44O7/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-23-29(35)28-26(36-2)21-27(37-3)31(38-4)32(28)39-30(23)22-18-19-24(33)25(34)20-22/h18-21,33-34H,5-17H2,1-4H3
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n/an/a 115n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012452
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexyloxy-5,6,7-trimetho...)
Show SMILES CCCCCCOc1c(oc2cc(OC)c(OC)c(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C24H28O8/c1-5-6-7-8-11-31-24-20(27)19-17(13-18(28-2)22(29-3)23(19)30-4)32-21(24)14-9-10-15(25)16(26)12-14/h9-10,12-13,25-26H,5-8,11H2,1-4H3
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n/an/a 126n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012463
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hexyloxy-3,7,8-trimetho...)
Show SMILES CCCCCCOc1cc(OC)c(OC)c2oc(-c3ccc(O)c(O)c3)c(OC)c(=O)c12
Show InChI InChI=1S/C24H28O8/c1-5-6-7-8-11-31-17-13-18(28-2)22(29-3)23-19(17)20(27)24(30-4)21(32-23)14-9-10-15(25)16(26)12-14/h9-10,12-13,25-26H,5-8,11H2,1-4H3
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n/an/a 128n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012449
PNG
(3-Decyl-2-(3,4-dihydroxy-phenyl)-5-hydroxy-7,8-dim...)
Show SMILES CCCCCCCCCCc1c(oc2c(OC)c(OC)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C27H34O7/c1-4-5-6-7-8-9-10-11-12-18-24(31)23-21(30)16-22(32-2)26(33-3)27(23)34-25(18)17-13-14-19(28)20(29)15-17/h13-16,28-30H,4-12H2,1-3H3
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n/an/a 135n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012469
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7,8-dimethoxy-3...)
Show SMILES CCCCCCCCc1c(oc2c(OC)c(OC)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C25H30O7/c1-4-5-6-7-8-9-10-16-22(29)21-19(28)14-20(30-2)24(31-3)25(21)32-23(16)15-11-12-17(26)18(27)13-15/h11-14,26-28H,4-10H2,1-3H3
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n/an/a 140n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012471
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-6,7-dimethoxy-3...)
Show SMILES CCCCCCCCc1c(O)c2c(cc(OC)c(OC)c2=O)oc1-c1ccc(O)c(O)c1
Show InChI InChI=1S/C25H30O7/c1-4-5-6-7-8-9-10-16-22(28)21-19(14-20(30-2)25(31-3)23(21)29)32-24(16)15-11-12-17(26)18(27)13-15/h11-14,26-28H,4-10H2,1-3H3
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n/an/a 155n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012438
PNG
(2-(3,4-Dihydroxy-phenyl)-3-dodecyl-5,6,7-trimethox...)
Show SMILES CCCCCCCCCCCCc1c(oc2cc(OC)c(OC)c(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C30H40O7/c1-5-6-7-8-9-10-11-12-13-14-15-21-27(33)26-24(19-25(34-2)29(35-3)30(26)36-4)37-28(21)20-16-17-22(31)23(32)18-20/h16-19,31-32H,5-15H2,1-4H3
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n/an/a 175n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of Arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012457
PNG
(3-Decyl-2-(3,4-dihydroxy-phenyl)-5,6,7-trimethoxy-...)
Show SMILES CCCCCCCCCCc1c(oc2cc(OC)c(OC)c(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C28H36O7/c1-5-6-7-8-9-10-11-12-13-19-25(31)24-22(17-23(32-2)27(33-3)28(24)34-4)35-26(19)18-14-15-20(29)21(30)16-18/h14-17,29-30H,5-13H2,1-4H3
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n/an/a 190n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of Arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012464
PNG
(2-(3,4-Dihydroxy-phenyl)-3-dodecyl-5-hydroxy-6,7-d...)
Show SMILES CCCCCCCCCCCCc1c(O)c2c(cc(OC)c(OC)c2=O)oc1-c1ccc(O)c(O)c1
Show InChI InChI=1S/C29H38O7/c1-4-5-6-7-8-9-10-11-12-13-14-20-26(32)25-23(18-24(34-2)29(35-3)27(25)33)36-28(20)19-15-16-21(30)22(31)17-19/h15-18,30-32H,4-14H2,1-3H3
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n/an/a 210n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of Arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012466
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexyl-5,6,7-trimethoxy-...)
Show SMILES CCCCCCc1c(oc2cc(OC)c(OC)c(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C24H28O7/c1-5-6-7-8-9-15-21(27)20-18(13-19(28-2)23(29-3)24(20)30-4)31-22(15)14-10-11-16(25)17(26)12-14/h10-13,25-26H,5-9H2,1-4H3
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n/an/a 220n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012453
PNG
(2-(3,4-Dihydroxy-phenyl)-5,6,7-trimethoxy-3-tetrad...)
Show SMILES CCCCCCCCCCCCCCc1c(oc2cc(OC)c(OC)c(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C32H44O7/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-23-29(35)28-26(21-27(36-2)31(37-3)32(28)38-4)39-30(23)22-18-19-24(33)25(34)20-22/h18-21,33-34H,5-17H2,1-4H3
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n/an/a 240n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of Arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012468
PNG
(2-(3,4-Dihydroxy-phenyl)-5,6,7-trimethoxy-3-octyl-...)
Show SMILES CCCCCCCCc1c(oc2cc(OC)c(OC)c(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C26H32O7/c1-5-6-7-8-9-10-11-17-23(29)22-20(15-21(30-2)25(31-3)26(22)32-4)33-24(17)16-12-13-18(27)19(28)14-16/h12-15,27-28H,5-11H2,1-4H3
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n/an/a 250n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of Arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012462
PNG
(3-Butyl-2-(3,4-dihydroxy-phenyl)-5-hydroxy-6,7-dim...)
Show SMILES CCCCc1c(O)c2c(cc(OC)c(OC)c2=O)oc1-c1ccc(O)c(O)c1
Show InChI InChI=1S/C21H22O7/c1-4-5-6-12-18(24)17-15(10-16(26-2)21(27-3)19(17)25)28-20(12)11-7-8-13(22)14(23)9-11/h7-10,22-24H,4-6H2,1-3H3
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n/an/a 265n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012458
PNG
(3-Decyl-2-(3,4-dihydroxy-phenyl)-5-hydroxy-6,7-dim...)
Show SMILES CCCCCCCCCCc1c(O)c2c(cc(OC)c(OC)c2=O)oc1-c1ccc(O)c(O)c1
Show InChI InChI=1S/C27H34O7/c1-4-5-6-7-8-9-10-11-12-18-24(30)23-21(16-22(32-2)27(33-3)25(23)31)34-26(18)17-13-14-19(28)20(29)15-17/h13-16,28-30H,4-12H2,1-3H3
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n/an/a 270n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of Arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012440
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hexyloxy-3,6,7-trimetho...)
Show SMILES CCCCCCOc1c(OC)c(OC)cc2oc(-c3ccc(O)c(O)c3)c(OC)c(=O)c12
Show InChI InChI=1S/C24H28O8/c1-5-6-7-8-11-31-23-19-17(13-18(28-2)22(23)29-3)32-21(24(30-4)20(19)27)14-9-10-15(25)16(26)12-14/h9-10,12-13,25-26H,5-8,11H2,1-4H3
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n/an/a 280n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012448
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7,8-dimethoxy-3...)
Show SMILES COc1cc(O)c2c(oc(c(C)c2=O)-c2ccc(O)c(O)c2)c1OC
Show InChI InChI=1S/C18H16O7/c1-8-15(22)14-12(21)7-13(23-2)17(24-3)18(14)25-16(8)9-4-5-10(19)11(20)6-9/h4-7,19-21H,1-3H3
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n/an/a 300n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012455
PNG
(2-(3,4-Dihydroxy-phenyl)-3-dodecyl-5-hydroxy-7,8-d...)
Show SMILES CCCCCCCCCCCCc1c(oc2c(OC)c(OC)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C29H38O7/c1-4-5-6-7-8-9-10-11-12-13-14-20-26(33)25-23(32)18-24(34-2)28(35-3)29(25)36-27(20)19-15-16-21(30)22(31)17-19/h15-18,30-32H,4-14H2,1-3H3
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n/an/a 340n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of Arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012443
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexyloxy-5-hydroxy-7,8-...)
Show SMILES CCCCCCOc1c(oc2c(OC)c(OC)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C23H26O8/c1-4-5-6-7-10-30-23-19(27)18-16(26)12-17(28-2)21(29-3)22(18)31-20(23)13-8-9-14(24)15(25)11-13/h8-9,11-12,24-26H,4-7,10H2,1-3H3
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n/an/a 350n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012445
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexyloxy-5-hydroxy-6,7-...)
Show SMILES CCCCCCOc1c(oc2cc(OC)c(OC)c(O)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C23H26O8/c1-4-5-6-7-10-30-23-20(27)18-16(12-17(28-2)22(29-3)19(18)26)31-21(23)13-8-9-14(24)15(25)11-13/h8-9,11-12,24-26H,4-7,10H2,1-3H3
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n/an/a 480n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012472
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-6,7-dimethoxy-3...)
Show SMILES COc1cc2oc(c(C)c(=O)c2c(O)c1OC)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C18H16O7/c1-8-15(21)14-12(7-13(23-2)18(24-3)16(14)22)25-17(8)9-4-5-10(19)11(20)6-9/h4-7,19-20,22H,1-3H3
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n/an/a 480n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012441
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexadecyl-5,7,8-trimeth...)
Show SMILES CCCCCCCCCCCCCCCCc1c(oc2c(OC)c(OC)cc(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C34H48O7/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25-31(37)30-28(38-2)23-29(39-3)33(40-4)34(30)41-32(25)24-20-21-26(35)27(36)22-24/h20-23,35-36H,5-19H2,1-4H3
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n/an/a 500n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012474
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7,8-dimethoxy-3...)
Show SMILES CCCCCCCCCCCCCCc1c(oc2c(OC)c(OC)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C31H42O7/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-22-28(35)27-25(34)20-26(36-2)30(37-3)31(27)38-29(22)21-17-18-23(32)24(33)19-21/h17-20,32-34H,4-16H2,1-3H3
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n/an/a 500n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of Arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012454
PNG
(3-Butyl-2-(3,4-dihydroxy-phenyl)-5,6,7-trimethoxy-...)
Show SMILES CCCCc1c(oc2cc(OC)c(OC)c(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C22H24O7/c1-5-6-7-13-19(25)18-16(11-17(26-2)21(27-3)22(18)28-4)29-20(13)12-8-9-14(23)15(24)10-12/h8-11,23-24H,5-7H2,1-4H3
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n/an/a 500n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012444
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hexyloxy-3-hydroxy-7,8-...)
Show SMILES CCCCCCOc1cc(OC)c(OC)c2oc(-c3ccc(O)c(O)c3)c(O)c(=O)c12
Show InChI InChI=1S/C23H26O8/c1-4-5-6-7-10-30-16-12-17(28-2)22(29-3)23-18(16)19(26)20(27)21(31-23)13-8-9-14(24)15(25)11-13/h8-9,11-12,24-25,27H,4-7,10H2,1-3H3
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n/an/a 770n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012470
PNG
(2-(3,4-Dihydroxy-phenyl)-5,7,8-trimethoxy-3-methyl...)
Show SMILES COc1cc(OC)c2c(oc(c(C)c2=O)-c2ccc(O)c(O)c2)c1OC
Show InChI InChI=1S/C19H18O7/c1-9-16(22)15-13(23-2)8-14(24-3)18(25-4)19(15)26-17(9)10-5-6-11(20)12(21)7-10/h5-8,20-21H,1-4H3
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n/an/a 800n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012439
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-6,7-dimethoxy-3...)
Show SMILES CCCCCCCCCCCCCCc1c(O)c2c(cc(OC)c(OC)c2=O)oc1-c1ccc(O)c(O)c1
Show InChI InChI=1S/C31H42O7/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-22-28(34)27-25(20-26(36-2)31(37-3)29(27)35)38-30(22)21-17-18-23(32)24(33)19-21/h17-20,32-34H,4-16H2,1-3H3
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n/an/a 870n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012446
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexadecyl-5,6,7-trimeth...)
Show SMILES CCCCCCCCCCCCCCCCc1c(oc2cc(OC)c(OC)c(OC)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C34H48O7/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25-31(37)30-28(23-29(38-2)33(39-3)34(30)40-4)41-32(25)24-20-21-26(35)27(36)22-24/h20-23,35-36H,5-19H2,1-4H3
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n/an/a 950n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012460
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexadecyl-5-hydroxy-6,7...)
Show SMILES CCCCCCCCCCCCCCCCc1c(O)c2c(cc(OC)c(OC)c2=O)oc1-c1ccc(O)c(O)c1
Show InChI InChI=1S/C33H46O7/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24-30(36)29-27(22-28(38-2)33(39-3)31(29)37)40-32(24)23-19-20-25(34)26(35)21-23/h19-22,34-36H,4-18H2,1-3H3
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n/an/a 1.25E+3n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012442
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hexyloxy-3-hydroxy-6,7-...)
Show SMILES CCCCCCOc1c(OC)c(OC)cc2oc(-c3ccc(O)c(O)c3)c(O)c(=O)c12
Show InChI InChI=1S/C23H26O8/c1-4-5-6-7-10-30-23-18-16(12-17(28-2)22(23)29-3)31-21(20(27)19(18)26)13-8-9-14(24)15(25)11-13/h8-9,11-12,24-25,27H,4-7,10H2,1-3H3
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n/an/a 1.35E+3n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012459
PNG
(2-(3,4-Dihydroxy-phenyl)-5,6,7-trimethoxy-3-methyl...)
Show SMILES COc1cc2oc(c(C)c(=O)c2c(OC)c1OC)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C19H18O7/c1-9-16(22)15-13(8-14(23-2)18(24-3)19(15)25-4)26-17(9)10-5-6-11(20)12(21)7-10/h5-8,20-21H,1-4H3
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n/an/a 1.40E+3n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012467
PNG
(2-(3,4-Dihydroxy-phenyl)-3-hexadecyl-5-hydroxy-7,8...)
Show SMILES CCCCCCCCCCCCCCCCc1c(oc2c(OC)c(OC)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C33H46O7/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24-30(37)29-27(36)22-28(38-2)32(39-3)33(29)40-31(24)23-19-20-25(34)26(35)21-23/h19-22,34-36H,4-18H2,1-3H3
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n/an/a 1.50E+3n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%