Affinity Data by PubMed id=20826091

PubMed code 20826091

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM18692 ((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-f...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universität Leipzig Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in human CV1 cells assessed as inhibition of receptor-mediated transactivation by MMTV-lucif...				Bioorg Med Chem 18: 6960-9 (2010) Article DOI: 10.1016/j.bmc.2010.08.029 BindingDB Entry DOI: 10.7270/Q2WW7HW5
Universität Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50327040 (17-[(6S)-6-Methyl-5,6-dihydropyridin-2(1H)-one-6-y...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universität Leipzig Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in human CV1 cells assessed as inhibition of receptor-mediated transactivation by MMTV-lucif...				Bioorg Med Chem 18: 6960-9 (2010) Article DOI: 10.1016/j.bmc.2010.08.029 BindingDB Entry DOI: 10.7270/Q2WW7HW5
Universität Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50327043 (17-[(6R)-6-Methyl-5,6-dihydropyridin-2(1H)-one-6-y...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Leipzig Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in human CV1 cells assessed as inhibition of receptor-mediated transactivation by MMTV-lucif...				Bioorg Med Chem 18: 6960-9 (2010) Article DOI: 10.1016/j.bmc.2010.08.029 BindingDB Entry DOI: 10.7270/Q2WW7HW5
Universität Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50327042 (17-[(6R)-6-Methyl-5,6-dihydropyridin-2(1H)-one-6-y...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Leipzig Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in human CV1 cells assessed as inhibition of receptor-mediated transactivation by MMTV-lucif...				Bioorg Med Chem 18: 6960-9 (2010) Article DOI: 10.1016/j.bmc.2010.08.029 BindingDB Entry DOI: 10.7270/Q2WW7HW5
Universität Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50327041 (17-[(6S)-6-Methyl-5,6-dihydropyridin-2(1H)-one-6-y...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Leipzig Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in human CV1 cells assessed as inhibition of receptor-mediated transactivation by MMTV-lucif...				Bioorg Med Chem 18: 6960-9 (2010) Article DOI: 10.1016/j.bmc.2010.08.029 BindingDB Entry DOI: 10.7270/Q2WW7HW5
Universität Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50131270 (2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universität Leipzig Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in human CV1 cells assessed as inhibition of receptor-mediated transactivation by MMTV-lucif...				Bioorg Med Chem 18: 6960-9 (2010) Article DOI: 10.1016/j.bmc.2010.08.029 BindingDB Entry DOI: 10.7270/Q2WW7HW5
Universität Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%