Affinity Data by PubMed id=21036612

PubMed code 21036612

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50331744 ((S)-1-(2-amino-2-carboxyethyl)-1H-1,2,3-triazole-4...) Show SMILES N[C@@H](Cn1cc(nn1)C(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50331745 ((S)-2-amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50331745 ((S)-2-amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR4 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50331746 ((S)-2-amino-3-(1-(carboxymethyl)-1H-1,2,3-triazol-...) Show SMILES N[C@@H](Cc1cnnn1CC(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50331748 ((S)-2-amino-3-(1-(carboxymethyl)-1H-1,2,3-triazol-...) Show SMILES N[C@@H](Cc1cn(CC(O)=O)nn1)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR4 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50331747 ((S)-2-amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50331747 ((S)-2-amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR4 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50331744 ((S)-1-(2-amino-2-carboxyethyl)-1H-1,2,3-triazole-4...) Show SMILES N[C@@H](Cn1cc(nn1)C(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR4 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50331746 ((S)-2-amino-3-(1-(carboxymethyl)-1H-1,2,3-triazol-...) Show SMILES N[C@@H](Cc1cnnn1CC(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR4 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50331748 ((S)-2-amino-3-(1-(carboxymethyl)-1H-1,2,3-triazol-...) Show SMILES N[C@@H](Cc1cn(CC(O)=O)nn1)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 mins				Bioorg Med Chem Lett 20: 7512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.139 BindingDB Entry DOI: 10.7270/Q2K64J94
The University of Adelaide Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%