Affinity Data by PubMed id=21067438

PubMed code 21067438

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM234404 (3,4-Dimethoxycinnamoylcholine chloride (1)) Show SMILES COc1ccc(\C=C\C(=O)OCC[N+](C)(C)C)cc1OC Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM234405 (Cinnamoylcholine chloride (2)) Show SMILES C[N+](C)(C)CCOC(=O)\C=C\c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM234406 (Caffeoylcholine trifluoroacetate (3)) Show SMILES C[N+](C)(C)CCOC(=O)\C=C\c1ccc(O)c(O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM234407 (Rosmarinylcholine trifluoroacetate (4)) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM234408 (Troloxcholine trifluoroacetate (5)) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.19E+6	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50059986 (3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydroxyph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.22E+6	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50359629 (TROLOX) Show SMILES Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+6	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM4375 ((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid \| (2...) Show SMILES OC(=O)\C=C\c1ccc(O)c(O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.55E+6	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50341141 ((E)-3,4-dimethoxycinnamic acid \| (E)-3-(3,4-Dimeth...) Show SMILES COc1ccc(\C=C\C(O)=O)cc1OC Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.20E+6	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM16430 ((2E)-3-phenylprop-2-enoic acid \| CHEMBL27246 \| Cin...) Show SMILES OC(=O)\C=C\c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	9.90E+6	n/a	n/a	n/a	n/a	8.0	n/a
Instituto Superior T�cnico					Assay Description AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...				J Enzyme Inhib Med Chem 26: 485-97 (2011) Article DOI: 10.3109/14756366.2010.529806 BindingDB Entry DOI: 10.7270/Q2862FBS
Instituto Superior T�cnico					More data for this Ligand-Target Pair

* indicates data uncertainty>20%