Affinity Data by PubMed id=21300544

PubMed code 21300544

Found 19 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50142887 (1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...) Show SMILES CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(N)ncnc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337691 (1-(2-(4-Hexyl-1H-1,2,3-triazol-1-yl)ethyl)-3-pheny...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337693 (1-(2-Azidoethyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337678 (3-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337677 (CHEMBL1683309 \| Ethyl 2-(4-((4-amino-3-phenyl-1H-p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337680 (2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337688 (1-(2-(4-(4-Methoxyphenyl)-1H-1,2,3-triazol-1-yl)et...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337681 (2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337687 (1-(2-(4-(4-Fluorophenyl)-1H-1,2,3-triazol-1-yl)eth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337685 (2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337686 (1-(4-(1-(2-(4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyr...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337689 (1-(2-(4-Decyl-1H-1,2,3-triazol-1-yl)ethyl)-3-pheny...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337683 (2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337692 (1-(2-(4-Butyl-1H-1,2,3-triazol-1-yl)ethyl)-3-pheny...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337684 (2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337690 (1-(2-(4-Heptyl-1H-1,2,3-triazol-1-yl)ethyl)-3-phen...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337679 (2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50337682 (2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of GST-fussed c-SRC after 30 mins				Bioorg Med Chem Lett 21: 1342-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.047 BindingDB Entry DOI: 10.7270/Q2P84C6B
Institute of Technology and Science Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%