Found 26 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116537
(3-({3-[4-(Biphenyl-4-yloxy)-phenoxy]-propyl}-methy...)Show SMILES CN(CCCOc1ccc(Oc2ccc(cc2)-c2ccccc2)cc1)CCC(O)=O Show InChI InChI=1S/C25H27NO4/c1-26(18-16-25(27)28)17-5-19-29-22-12-14-24(15-13-22)30-23-10-8-21(9-11-23)20-6-3-2-4-7-20/h2-4,6-15H,5,16-19H2,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116560
(3-{Methyl-[3-(4-thiophen-3-ylmethyl-phenoxy)-propy...)Show InChI InChI=1S/C18H23NO3S/c1-19(10-7-18(20)21)9-2-11-22-17-5-3-15(4-6-17)13-16-8-12-23-14-16/h3-6,8,12,14H,2,7,9-11,13H2,1H3,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50342776
(4-((3-(4-(biphenyl-4-yloxy)phenylamino)-6-azabicyc...)Show SMILES OC(=O)c1ccc(CN2CC3CC(Nc4ccc(Oc5ccc(cc5)-c5ccccc5)cc4)C2CCC3)cc1 |THB:7:8:12.11:34.35.36| Show InChI InChI=1S/C34H34N2O3/c37-34(38)28-11-9-24(10-12-28)22-36-23-25-5-4-8-33(36)32(21-25)35-29-15-19-31(20-16-29)39-30-17-13-27(14-18-30)26-6-2-1-3-7-26/h1-3,6-7,9-20,25,32-33,35H,4-5,8,21-23H2,(H,37,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251446
(4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H31N3O4/c1-29(19-21-9-11-22(12-10-21)27(32)33)17-6-18-30(2)20-26(31)28-23-13-15-25(16-14-23)34-24-7-4-3-5-8-24/h3-5,7-16H,6,17-20H2,1-2H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251500
(4-(((2,2-dimethyl-3-(methyl(2-oxo-2-(4-phenoxyphen...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)CC(C)(C)CN(C)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H35N3O4/c1-29(2,20-31(3)18-22-10-12-23(13-11-22)28(34)35)21-32(4)19-27(33)30-24-14-16-26(17-15-24)36-25-8-6-5-7-9-25/h5-17H,18-21H2,1-4H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50342777
(4-((3-(4-(benzo[d]thiazol-2-yloxy)phenylamino)-6-a...)Show SMILES OC(=O)c1ccc(CN2CC3CC(Nc4ccc(Oc5nc6ccccc6s5)cc4)C2CCC3)cc1 |THB:7:8:12.11:31.32.33| Show InChI InChI=1S/C29H29N3O3S/c33-28(34)21-10-8-19(9-11-21)17-32-18-20-4-3-6-26(32)25(16-20)30-22-12-14-23(15-13-22)35-29-31-24-5-1-2-7-27(24)36-29/h1-2,5,7-15,20,25-26,30H,3-4,6,16-18H2,(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50125420
(5-[2-(4-Benzyl-phenoxy)-ethyl]-5H-imidazo[4,5-c]py...)Show InChI InChI=1S/C21H19N3O/c1-2-4-17(5-3-1)14-18-6-8-19(9-7-18)25-13-12-24-11-10-20-21(15-24)23-16-22-20/h1-11,15-16H,12-14H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251501
(4-((methyl(2-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H29N3O4/c1-28(18-20-8-10-21(11-9-20)26(31)32)16-17-29(2)19-25(30)27-22-12-14-24(15-13-22)33-23-6-4-3-5-7-23/h3-15H,16-19H2,1-2H3,(H,27,30)(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116531
(3-[4-(4-Benzyl-phenoxy)-butylamino]-propionic acid...)Show InChI InChI=1S/C20H25NO3/c22-20(23)12-14-21-13-4-5-15-24-19-10-8-18(9-11-19)16-17-6-2-1-3-7-17/h1-3,6-11,21H,4-5,12-16H2,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251825
(4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCCN(C)CC(=O)Nc1ccc(Oc2ccccc2)cc1)CC1CCC(CC1)C(O)=O |(7.49,-15.66,;7.49,-14.12,;6.16,-13.35,;4.83,-14.12,;3.49,-13.35,;2.16,-14.12,;2.16,-15.66,;.83,-13.35,;-.51,-14.11,;-.51,-15.65,;-1.84,-13.34,;-3.18,-14.11,;-4.52,-13.34,;-5.85,-14.11,;-5.85,-15.66,;-7.18,-16.43,;-8.51,-15.65,;-9.85,-16.43,;-11.18,-15.66,;-11.18,-14.12,;-9.83,-13.35,;-8.51,-14.12,;-4.52,-16.43,;-3.18,-15.66,;8.83,-13.35,;10.16,-14.12,;10.15,-15.66,;11.48,-16.43,;12.81,-15.67,;12.82,-14.13,;11.49,-13.35,;14.15,-16.45,;14.14,-17.99,;15.48,-15.68,)| Show InChI InChI=1S/C27H37N3O4/c1-29(19-21-9-11-22(12-10-21)27(32)33)17-6-18-30(2)20-26(31)28-23-13-15-25(16-14-23)34-24-7-4-3-5-8-24/h3-5,7-8,13-16,21-22H,6,9-12,17-20H2,1-2H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121023
(1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidin-3-ol | C...)Show InChI InChI=1S/C19H23NO2/c21-18-10-11-20(15-18)12-13-22-19-8-6-17(7-9-19)14-16-4-2-1-3-5-16/h1-9,18,21H,10-15H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251387
(2-(Methyl-{3-[methyl-(4-sulfamoyl-benzyl)-amino]-p...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)S(N)(=O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H32N4O4S/c1-29(19-21-9-15-25(16-10-21)35(27,32)33)17-6-18-30(2)20-26(31)28-22-11-13-24(14-12-22)34-23-7-4-3-5-8-23/h3-5,7-16H,6,17-20H2,1-2H3,(H,28,31)(H2,27,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50085255
(2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl...)Show InChI InChI=1S/C21H22N2O3/c1-2-13-23(12-1)14-16-24-18-7-9-20(10-8-18)26-19-5-3-17(4-6-19)21-22-11-15-25-21/h3-11,15H,1-2,12-14,16H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121008
(CHEMBL114563 | N-{1-[2-(4-Benzyl-phenoxy)-ethyl]-p...)Show InChI InChI=1S/C22H28N2O2/c1-18(25)23-21-11-13-24(14-12-21)15-16-26-22-9-7-20(8-10-22)17-19-5-3-2-4-6-19/h2-10,21H,11-17H2,1H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121005
(CHEMBL115227 | {1-[2-(4-Benzyl-phenoxy)-ethyl]-pip...)Show InChI InChI=1S/C21H27N3O2/c22-21(25)23-19-10-12-24(13-11-19)14-15-26-20-8-6-18(7-9-20)16-17-4-2-1-3-5-17/h1-9,19H,10-16H2,(H3,22,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116557
(CHEMBL117455 | {[4-(4-Benzyl-phenoxy)-butyl]-methy...)Show InChI InChI=1S/C20H25NO3/c1-21(16-20(22)23)13-5-6-14-24-19-11-9-18(10-12-19)15-17-7-3-2-4-8-17/h2-4,7-12H,5-6,13-16H2,1H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116540
(3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic aci...)Show InChI InChI=1S/C19H23NO3/c21-19(22)11-13-20-12-4-14-23-18-9-7-17(8-10-18)15-16-5-2-1-3-6-16/h1-3,5-10,20H,4,11-15H2,(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50085266
(4-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazole |...)Show InChI InChI=1S/C16H20N2OS/c1-2-8-18(7-1)9-10-19-16-5-3-14(4-6-16)11-15-12-20-13-17-15/h3-6,12-13H,1-2,7-11H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116547
(3-[2-(4-Benzyl-phenoxy)-ethylamino]-propionic acid...)Show InChI InChI=1S/C19H23NO3/c1-22-19(21)11-12-20-13-14-23-18-9-7-17(8-10-18)15-16-5-3-2-4-6-16/h2-10,20H,11-15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50285633
((R)-3-Benzyl-N-((S)-1-carboxy-ethyl)-succinamic ac...)Show SMILES C[C@H](NC(=O)[C@@H](CC(O)=O)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C14H17NO5/c1-9(14(19)20)15-13(18)11(8-12(16)17)7-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/t9-,11+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121013
((S)-1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidine-2-c...)Show InChI InChI=1S/C21H25NO3/c1-24-21(23)20-8-5-13-22(20)14-15-25-19-11-9-18(10-12-19)16-17-6-3-2-4-7-17/h2-4,6-7,9-12,20H,5,8,13-16H2,1H3/t20-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50085258
(2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl...)Show SMILES C(CN1CCCC1)Oc1ccc(Oc2ccc(cc2)C2=NCCO2)cc1 |t:21| Show InChI InChI=1S/C21H24N2O3/c1-2-13-23(12-1)14-16-24-18-7-9-20(10-8-18)26-19-5-3-17(4-6-19)21-22-11-15-25-21/h3-10H,1-2,11-16H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116543
(3-{Methyl-[3-(4-pyridin-3-ylmethyl-phenoxy)-propyl...)Show InChI InChI=1S/C20H26N2O3/c1-22(13-10-20(23)24-2)12-4-14-25-19-8-6-17(7-9-19)15-18-5-3-11-21-16-18/h3,5-9,11,16H,4,10,12-15H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50085254
(1-[2-(4-Benzyl-2-chloro-phenoxy)-ethyl]-pyrrolidin...)Show InChI InChI=1S/C19H22ClNO/c20-18-15-17(14-16-6-2-1-3-7-16)8-9-19(18)22-13-12-21-10-4-5-11-21/h1-3,6-9,15H,4-5,10-14H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50285634
((R)-1-((R)-2-Benzyl-3-hydroxycarbamoyl-propionyl)-...)Show SMILES ONC(=O)C[C@@H](Cc1ccccc1)C(=O)N1CCCC[C@@H]1C(O)=O Show InChI InChI=1S/C17H22N2O5/c20-15(18-24)11-13(10-12-6-2-1-3-7-12)16(21)19-9-5-4-8-14(19)17(22)23/h1-3,6-7,13-14,24H,4-5,8-11H2,(H,18,20)(H,22,23)/t13-,14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50085257
(1-[2-(4-Phenylmethanesulfonyl-phenoxy)-ethyl]-pyrr...)Show InChI InChI=1S/C19H23NO3S/c21-24(22,16-17-6-2-1-3-7-17)19-10-8-18(9-11-19)23-15-14-20-12-4-5-13-20/h1-3,6-11H,4-5,12-16H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description
Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007
BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this
Ligand-Target Pair | |
Search and Browse
