Affinity Data by PubMed id=21420859

PubMed code 21420859

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Pomezia Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells by fluorescent activity assay				Bioorg Med Chem Lett 21: 2305-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.085 BindingDB Entry DOI: 10.7270/Q2VQ35HJ
Menarini Ricerche Pomezia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase (Homo sapiens (Human))	BDBM50483618 (CHEMBL1760915) Show SMILES ONC(=O)CCCC1CCN(CC1)C(=O)NCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Pomezia Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells by fluorescent activity assay				Bioorg Med Chem Lett 21: 2305-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.085 BindingDB Entry DOI: 10.7270/Q2VQ35HJ
Menarini Ricerche Pomezia Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50483617 (CHEMBL1760914) Show SMILES ONC(=O)CCCC1CCN(CC1)C(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Pomezia Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells by fluorescent activity assay				Bioorg Med Chem Lett 21: 2305-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.085 BindingDB Entry DOI: 10.7270/Q2VQ35HJ
Menarini Ricerche Pomezia Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50483619 (CHEMBL1760913) Show SMILES ONC(=O)CCCC1CCN(CC1)C(=O)Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Pomezia Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells by fluorescent activity assay				Bioorg Med Chem Lett 21: 2305-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.085 BindingDB Entry DOI: 10.7270/Q2VQ35HJ
Menarini Ricerche Pomezia Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50483615 (CHEMBL1760911) Show SMILES ONC(=O)CCCC1CCN(CC1)S(=O)(=O)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Pomezia Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells by fluorescent activity assay				Bioorg Med Chem Lett 21: 2305-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.085 BindingDB Entry DOI: 10.7270/Q2VQ35HJ
Menarini Ricerche Pomezia Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50483614 (CHEMBL1760910) Show SMILES ONC(=O)CCCC1CCN(CC1)S(=O)(=O)Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Pomezia Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells by fluorescent activity assay				Bioorg Med Chem Lett 21: 2305-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.085 BindingDB Entry DOI: 10.7270/Q2VQ35HJ
Menarini Ricerche Pomezia Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50483616 (CHEMBL1760912) Show SMILES ONC(=O)CCCC1CCN(CC1)C(=O)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Pomezia Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells by fluorescent activity assay				Bioorg Med Chem Lett 21: 2305-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.085 BindingDB Entry DOI: 10.7270/Q2VQ35HJ
Menarini Ricerche Pomezia Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%