Affinity Data by PubMed id=2153214

PubMed code 2153214

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	7.4	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description In vitro binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptic membranes at pH 7.4				J Med Chem 33: 71-7 (1990) BindingDB Entry DOI: 10.7270/Q2RV0P9C
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50013223 (CHEMBL349005 \| Pyrrolidin-3-yl-acetic acid ((S)-(+...) Show SMILES OC(=O)C[C@@H]1CCNC1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	7.4	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description In vitro binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptic membranes at pH 7.4				J Med Chem 33: 71-7 (1990) BindingDB Entry DOI: 10.7270/Q2RV0P9C
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50013224 (CHEMBL351355 \| Pyrrolidin-3-yl-acetic acid \| Pyrro...) Show SMILES OC(=O)CC1CCNC1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	7.4	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description In vitro binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptic membranes at pH 7.4				J Med Chem 33: 71-7 (1990) BindingDB Entry DOI: 10.7270/Q2RV0P9C
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50367949 (CHEMBL1788265) Show SMILES OC(=O)C[C@H]1CCNC1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description In vitro binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptic membranes at pH 7.4				J Med Chem 33: 71-7 (1990) BindingDB Entry DOI: 10.7270/Q2RV0P9C
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%