Affinity Data by PubMed id=21561780

PubMed code 21561780

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485661 (Dalenin) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as inhibition constant for compound-free enzyme using as L-tyrosine substrate by spectrophotometric analys...				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485661 (Dalenin) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as inhibition constant for compound-enzyme-substrate complex using as L-tyrosine substrate by spectrophoto...				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as inhibition constant for compound-free enzyme using as L-tyrosine substrate by spectrophotometric analys...				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485661 (Dalenin) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as inhibition constant for compound-enzyme-substrate complex using as L-dopamine substrate by spectrophoto...				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485661 (Dalenin) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as inhibition constant for compound-free enzyme using as L-dopamine substrate by spectrophotometric analys...				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485661 (Dalenin) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-tyrosine substrate after 10 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50269605 (CHEMBL465194 \| steppogenin) Show SMILES Oc1ccc(C2CC(=O)c3c(O)cc(O)cc3O2)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-tyrosine substrate after 10 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485662 (CHEMBL2147166) Show SMILES CCCCC\C=C/C\C=C/CCCc1cc(O)cc(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM26190 (1,4-Dihydroxybenzene, XIII \| 1,4-dihydroxybenzene ...) Show SMILES Oc1ccc(O)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-tyrosine substrate after 10 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485661 (Dalenin) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50269605 (CHEMBL465194 \| steppogenin) Show SMILES Oc1ccc(C2CC(=O)c3c(O)cc(O)cc3O2)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485662 (CHEMBL2147166) Show SMILES CCCCC\C=C/C\C=C/CCCc1cc(O)cc(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-tyrosine substrate after 10 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50351096 (ASCORBIC ACID) Show SMILES OC[C@H](O)[C@H]1OC(=O)C(=O)C1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.46E+5	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM26991 (CHEMBL1689285 \| HSO3- \| bisulfite \| hydrogen sulfi...) Show SMILES OS([O-])=O Show InChI InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM26190 (1,4-Dihydroxybenzene, XIII \| 1,4-dihydroxybenzene ...) Show SMILES Oc1ccc(O)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.09E+6	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.30E+6	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysis				Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ
Catholic University of C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%