Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nuclear receptor subfamily 1 group I member 2 (Homo sapiens (Human)) | BDBM50347620 (RIFAXIMIN | Rifacol | Rifaxidin) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a |
Universita di Napoli Federico II Curated by ChEMBL | Assay Description Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assay | J Med Chem 54: 4590-9 (2011) Article DOI: 10.1021/jm200241s BindingDB Entry DOI: 10.7270/Q2W37WP3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 1 group I member 2 (Homo sapiens (Human)) | BDBM50347619 (CHEMBL1649712 | Solomonsterol A) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a |
Universita di Napoli Federico II Curated by ChEMBL | Assay Description Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assay | J Med Chem 54: 4590-9 (2011) Article DOI: 10.1021/jm200241s BindingDB Entry DOI: 10.7270/Q2W37WP3 | |||||||||||
More data for this Ligand-Target Pair |