Affinity Data by PubMed id=21612925

PubMed code 21612925

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345171 (CHEMBL1779738 \| N-((1H-Indol-3-yl)(phenyl)methyl)-...) Show SMILES CN(C(c1c[nH]c2ccccc12)c1ccccc1)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345179 (CHEMBL1779746 \| N-((1H-Indol-3-yl)(3-nitrophenyl)m...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345178 (CHEMBL1779745 \| N-Methyl-N-((1-methyl-1H-indol-3-y...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345180 (CHEMBL1779747 \| N-((5-Bromo-1H-indol-3-yl)(phenyl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345185 (CHEMBL1779752 \| N-((4-Chlorophenyl)(5-methoxy-1H-i...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345177 (CHEMBL1779744 \| N-((4-Chlorophenyl)(1-methyl-1H-in...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345181 (CHEMBL1779748 \| N-((5-Methoxy-1H-indol-3-yl)(4-met...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345184 (CHEMBL1779751 \| N-((5-bromo-1H-indol-3-yl)(4-metho...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345172 (CHEMBL1779739 \| N-((1H-Indol-3-yl)(4-hydroxy pheny...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345175 (CHEMBL1779742 \| N-((1H-Indol-3-yl)(2,4-dimethoxyph...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345182 (CHEMBL1779749 \| N-((5-Methoxy-1H-indol-3-yl)(p-tol...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345174 (CHEMBL1779741 \| N-((1H-Indol-3-yl)(3-methoxyphenyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345183 (CHEMBL1779750 \| N-((5-Bromo-1H-indol-3-yl)(p-tolyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345170 (CHEMBL1779737 \| N-((1H-Indol-3-yl)(4-methoxyphenyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345176 (CHEMBL1779743 \| N-Methyl-N-((1-methyl-1H-indol-3-y...) Show SMILES CN(C(c1cn(C)c2ccccc12)c1ccccc1)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345168 (CHEMBL1779735 \| N-((4-Chlorophenyl)(1H-indol-3-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345173 (CHEMBL1779740 \| N-((4-Hydroxy-3-bromophenyl)(1H-in...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50345169 (CHEMBL1779736 \| N-((1H-Indol-3-yl)(p-tolyl)methyl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
India Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of c-Src using AEEEIYGEFEAKKKK substrate by fluorescence intensity assay				Bioorg Med Chem Lett 21: 3511-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.010 BindingDB Entry DOI: 10.7270/Q2R49R44
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%