Affinity Data by PubMed id=21718029

PubMed code 21718029

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50350910 (CHEMBL1817964) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Area, PharmaMar SAU , Avenida de los Reyes 1, 28770-Colmenar Viejo, Madrid, Spain. Curated by ChEMBL					Assay Description Inhibition of EGFR-induced HIF1alpha activation in human HeLa cells preincubated for 1 hr prior to EGF stimulation by luciferase reporter gene assay				J Nat Prod 74: 1590-6 (2011) Article DOI: 10.1021/np200196j BindingDB Entry DOI: 10.7270/Q29C6XSZ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50350910 (CHEMBL1817964) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Area, PharmaMar SAU , Avenida de los Reyes 1, 28770-Colmenar Viejo, Madrid, Spain. Curated by ChEMBL					Assay Description Inhibition of EGFR-induced AP1 activation in human HeLa cells preincubated for 1 hr prior to EGF stimulation by luciferase reporter gene assay				J Nat Prod 74: 1590-6 (2011) Article DOI: 10.1021/np200196j BindingDB Entry DOI: 10.7270/Q29C6XSZ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50350910 (CHEMBL1817964) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Area, PharmaMar SAU , Avenida de los Reyes 1, 28770-Colmenar Viejo, Madrid, Spain. Curated by ChEMBL					Assay Description Inhibition of EGFR-induced Beta-catenin activation in human HeLa cells preincubated for 1 hr prior to EGF stimulation by luciferase reporter gene ass...				J Nat Prod 74: 1590-6 (2011) Article DOI: 10.1021/np200196j BindingDB Entry DOI: 10.7270/Q29C6XSZ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50350911 (CHEMBL1817965) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Area, PharmaMar SAU , Avenida de los Reyes 1, 28770-Colmenar Viejo, Madrid, Spain. Curated by ChEMBL					Assay Description Inhibition of EGFR-induced HIF1alpha activation in human HeLa cells preincubated for 1 hr prior to EGF stimulation by luciferase reporter gene assay				J Nat Prod 74: 1590-6 (2011) Article DOI: 10.1021/np200196j BindingDB Entry DOI: 10.7270/Q29C6XSZ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50350911 (CHEMBL1817965) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Area, PharmaMar SAU , Avenida de los Reyes 1, 28770-Colmenar Viejo, Madrid, Spain. Curated by ChEMBL					Assay Description Inhibition of EGFR-induced Beta-catenin activation in human HeLa cells preincubated for 1 hr prior to EGF stimulation by luciferase reporter gene ass...				J Nat Prod 74: 1590-6 (2011) Article DOI: 10.1021/np200196j BindingDB Entry DOI: 10.7270/Q29C6XSZ
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%