Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DNA ligase 1 (Homo sapiens (Human)) | BDBM50335293 ((2R,3R,4S,5R)-2-(6-amino-2-(butylthio)-9H-purin-9-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston Curated by ChEMBL | Assay Description Inhibition of human DNA Ligase I by FRET-based assay | Bioorg Med Chem Lett 21: 4556-60 (2011) Article DOI: 10.1016/j.bmcl.2011.05.128 BindingDB Entry DOI: 10.7270/Q24B31Q8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
