Affinity Data by PubMed id=21807511

PubMed code 21807511

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50352495 (CHEMBL1824555) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352496 (CHEMBL1824556) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352497 (CHEMBL1824553) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352498 (CHEMBL1824554) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352499 (CHEMBL1824551) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352500 (CHEMBL1824550) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352501 (CHEMBL1824559) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352502 (CHEMBL1824549) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352503 (CHEMBL1824552) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352504 (CHEMBL1824546) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352505 (CHEMBL1824544) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352506 (CHEMBL1824558) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.92E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50352507 (CHEMBL1824542) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human thrombin using chromogenic Sar-Pro-Arg p-nitroanilide dihydrochloride as substrate pre-incubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 21: 5305-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.023 BindingDB Entry DOI: 10.7270/Q23F4Q1P
The Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%