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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Proton-coupled folate transporter (Homo sapiens (Human)) | BDBM50354833 (AGF94 | CHEMBL1834488) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 5.5 by dixon plot analysis | J Med Chem 54: 7150-64 (2011) Article DOI: 10.1021/jm200739e BindingDB Entry DOI: 10.7270/Q2G16174 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proton-coupled folate transporter (Homo sapiens (Human)) | BDBM50354833 (AGF94 | CHEMBL1834488) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 6.8 | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 6.8 by dixon plot analysis | J Med Chem 54: 7150-64 (2011) Article DOI: 10.1021/jm200739e BindingDB Entry DOI: 10.7270/Q2G16174 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
