Affinity Data by PubMed id=21889235

PubMed code 21889235

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353749 (CHEMBL1828829) Show SMILES OC(=O)CCCCOc1ccc(cc1)C(=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.71E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353751 (CHEMBL1828831) Show SMILES CC(C)(CCCOc1ccc(Oc2ccccc2)cc1)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353753 (CHEMBL1828834) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.37E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353757 (CHEMBL1828826) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353754 (CHEMBL1828821) Show SMILES COc1cc(CC=C)ccc1OCCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353758 (CHEMBL1828827) Show SMILES OC(=O)CCCCOc1ccc(cc1)C(=O)\C=C\c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353750 (CHEMBL19641) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50099491 (2-(4-(2-(3-cyclohexyl-1-(4-cyclohexylbutyl)ureido)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353752 (CHEMBL1828832) Show SMILES OC(=O)CCCCOc1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353755 (CHEMBL1828822) Show SMILES COc1cc(CC=C)ccc1OCCCC(C)(C)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50110590 (2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure...) Show SMILES Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353756 (CHEMBL1828825) Show SMILES OC(=O)CCCCOc1ccc(\C=C\c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50353759 (CHEMBL1828828) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.15E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Agonist activity at Gal4-fused PPARalpha expressed in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Eur J Med Chem 46: 5218-24 (2011) Article DOI: 10.1016/j.ejmech.2011.08.022 BindingDB Entry DOI: 10.7270/Q2348KRV
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%