BindingDB logo
myBDB logout

PubMed code 21916484

Compile data set for download or QSAR
Found 41 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))		BDBM50355243
PNG
(CHEMBL1835836)
Show SMILES Cn1c(ccc1-c1ccc2oc(=O)ccc2c1)C#N
Show InChI InChI=1S/C15H10N2O2/c1-17-12(9-16)4-5-13(17)10-2-6-14-11(8-10)3-7-15(18)19-14/h2-8H,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 65n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355241
PNG
(CHEMBL1835834)
Show SMILES Clc1ccc(s1)-c1ccc2oc(=O)ccc2c1
Show InChI InChI=1S/C13H7ClO2S/c14-12-5-4-11(17-12)9-1-3-10-8(7-9)2-6-13(15)16-10/h1-7H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355237
PNG
(CHEMBL1835830)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc2oc(=O)ccc2c1
Show InChI InChI=1S/C16H9F3O2/c17-16(18,19)13-3-1-2-10(9-13)11-4-6-14-12(8-11)5-7-15(20)21-14/h1-9H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355234
PNG
(CHEMBL1835827)
Show SMILES Fc1ccc(cc1)-c1ccc2oc(=O)ccc2c1
Show InChI InChI=1S/C15H9FO2/c16-13-5-1-10(2-6-13)11-3-7-14-12(9-11)4-8-15(17)18-14/h1-9H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355239
PNG
(CHEMBL1835832)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1cccs1
Show InChI InChI=1S/C17H17NO2S/c1-3-18(4-2)14-11-15-12(7-8-17(19)20-15)10-13(14)16-6-5-9-21-16/h5-11H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355225
PNG
(CHEMBL1835818)
Show SMILES CN(C)c1cc2oc(=O)ccc2cc1-c1ccc(cc1)C#N
Show InChI InChI=1S/C18H14N2O2/c1-20(2)16-10-17-14(7-8-18(21)22-17)9-15(16)13-5-3-12(11-19)4-6-13/h3-10H,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355227
PNG
(CHEMBL1835820)
Show SMILES CN(C)c1cc2oc(=O)ccc2cc1-c1cccc(c1)C#N
Show InChI InChI=1S/C18H14N2O2/c1-20(2)16-10-17-14(6-7-18(21)22-17)9-15(16)13-5-3-4-12(8-13)11-19/h3-10H,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 260n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355244
PNG
(CHEMBL1835825)
Show SMILES O=c1ccc2cc(ccc2o1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H9NO2/c17-10-11-1-3-12(4-2-11)13-5-7-15-14(9-13)6-8-16(18)19-15/h1-9H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 290n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355233
PNG
(CHEMBL1835826)
Show SMILES CN(C)c1ccc(cc1)-c1ccc2oc(=O)ccc2c1
Show InChI InChI=1S/C17H15NO2/c1-18(2)15-7-3-12(4-8-15)13-5-9-16-14(11-13)6-10-17(19)20-16/h3-11H,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355224
PNG
(CHEMBL1835817)
Show SMILES CN(C)c1cc2oc(=O)ccc2cc1-c1ccccc1
Show InChI InChI=1S/C17H15NO2/c1-18(2)15-11-16-13(8-9-17(19)20-16)10-14(15)12-6-4-3-5-7-12/h3-11H,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 360n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355223
PNG
(CHEMBL1835816)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1cccc(c1)C#N
Show InChI InChI=1S/C20H18N2O2/c1-3-22(4-2)18-12-19-16(8-9-20(23)24-19)11-17(18)15-7-5-6-14(10-15)13-21/h5-12H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 380n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355220
PNG
(CHEMBL1835812)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C21H24N2O2/c1-5-23(6-2)19-14-20-16(9-12-21(24)25-20)13-18(19)15-7-10-17(11-8-15)22(3)4/h7-14H,5-6H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 390n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355221
PNG
(CHEMBL1835813)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(cc1)C(C)=O
Show InChI InChI=1S/C21H21NO3/c1-4-22(5-2)19-13-20-17(10-11-21(24)25-20)12-18(19)16-8-6-15(7-9-16)14(3)23/h6-13H,4-5H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355226
PNG
(CHEMBL1835819)
Show SMILES CN(C)c1cc2oc(=O)ccc2cc1-c1ccc(F)cc1
Show InChI InChI=1S/C17H14FNO2/c1-19(2)15-10-16-12(5-8-17(20)21-16)9-14(15)11-3-6-13(18)7-4-11/h3-10H,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 470n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355219
PNG
(CHEMBL1835811)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(NC(C)=O)cc1
Show InChI InChI=1S/C21H22N2O3/c1-4-23(5-2)19-13-20-16(8-11-21(25)26-20)12-18(19)15-6-9-17(10-7-15)22-14(3)24/h6-13H,4-5H2,1-3H3,(H,22,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 470n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355217
PNG
(CHEMBL1835808)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(cc1)C#N
Show InChI InChI=1S/C20H18N2O2/c1-3-22(4-2)18-12-19-16(9-10-20(23)24-19)11-17(18)15-7-5-14(13-21)6-8-15/h5-12H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355216
PNG
(CHEMBL1835807)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccccc1
Show InChI InChI=1S/C19H19NO2/c1-3-20(4-2)17-13-18-15(10-11-19(21)22-18)12-16(17)14-8-6-5-7-9-14/h5-13H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355246
PNG
(CHEMBL1835810)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(N)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C19H19N3O4/c1-3-21(4-2)16-11-18-13(6-8-19(23)26-18)9-14(16)12-5-7-15(20)17(10-12)22(24)25/h5-11H,3-4,20H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 510n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355232
PNG
(CHEMBL1650717)
Show SMILES O=c1ccc2cc(ccc2o1)-c1ccccc1
Show InChI InChI=1S/C15H10O2/c16-15-9-7-13-10-12(6-8-14(13)17-15)11-4-2-1-3-5-11/h1-10H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 510n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355240
PNG
(CHEMBL1835833)
Show SMILES O=c1ccc2cc(ccc2o1)-c1cccs1
Show InChI InChI=1S/C13H8O2S/c14-13-6-4-9-8-10(3-5-11(9)15-13)12-2-1-7-16-12/h1-8H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 540n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355236
PNG
(CHEMBL1835829)
Show SMILES Fc1cc(F)cc(c1)-c1ccc2oc(=O)ccc2c1
Show InChI InChI=1S/C15H8F2O2/c16-12-6-11(7-13(17)8-12)9-1-3-14-10(5-9)2-4-15(18)19-14/h1-8H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 560n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355222
PNG
(CHEMBL1835815)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(F)cc1
Show InChI InChI=1S/C19H18FNO2/c1-3-21(4-2)17-12-18-14(7-10-19(22)23-18)11-16(17)13-5-8-15(20)9-6-13/h5-12H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 630n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355245
PNG
(CHEMBL1835814)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H18ClNO2/c1-3-21(4-2)17-12-18-14(7-10-19(22)23-18)11-16(17)13-5-8-15(20)9-6-13/h5-12H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 770n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355218
PNG
(CHEMBL1835809)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C19H18N2O4/c1-3-20(4-2)17-12-18-14(7-10-19(22)25-18)11-16(17)13-5-8-15(9-6-13)21(23)24/h5-12H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 860n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355228
PNG
(CHEMBL1835821)
Show SMILES COc1cc2oc(=O)ccc2cc1-c1ccccc1
Show InChI InChI=1S/C16H12O3/c1-18-15-10-14-12(7-8-16(17)19-14)9-13(15)11-5-3-2-4-6-11/h2-10H,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 880n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355235
PNG
(CHEMBL1835828)
Show SMILES O=c1ccc2cc(ccc2o1)-c1cccc(c1)C#N
Show InChI InChI=1S/C16H9NO2/c17-10-11-2-1-3-12(8-11)13-4-6-15-14(9-13)5-7-16(18)19-15/h1-9H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.11E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355239
PNG
(CHEMBL1835832)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1cccs1
Show InChI InChI=1S/C17H17NO2S/c1-3-18(4-2)14-11-15-12(7-8-17(19)20-15)10-13(14)16-6-5-9-21-16/h5-11H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.24E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Displacement of [1,2,6,7-3H]PG from human PR-LBD after 24 hrs by liquid scintillation counting

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355242
PNG
(CHEMBL1835835)
Show SMILES O=c1ccc2cc(ccc2o1)-c1ccco1
Show InChI InChI=1S/C13H8O3/c14-13-6-4-10-8-9(3-5-12(10)16-13)11-2-1-7-15-11/h1-8H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.28E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355229
PNG
(CHEMBL1835822)
Show SMILES Oc1cc2oc(=O)ccc2cc1-c1ccccc1
Show InChI InChI=1S/C15H10O3/c16-13-9-14-11(6-7-15(17)18-14)8-12(13)10-4-2-1-3-5-10/h1-9,16H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.28E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355216
PNG
(CHEMBL1835807)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccccc1
Show InChI InChI=1S/C19H19NO2/c1-3-20(4-2)17-13-18-15(10-11-19(21)22-18)12-16(17)14-8-6-5-7-9-14/h5-13H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.42E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Displacement of [1,2,6,7-3H]PG from human PR-LBD after 24 hrs by liquid scintillation counting

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355231
PNG
(CHEMBL1835824)
Show SMILES CN(C)c1ccc(cc1)-c1cc2ccc(=O)oc2cc1O
Show InChI InChI=1S/C17H15NO3/c1-18(2)13-6-3-11(4-7-13)14-9-12-5-8-17(20)21-16(12)10-15(14)19/h3-10,19H,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.59E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355230
PNG
(CHEMBL1835823)
Show SMILES COc1cc2oc(=O)ccc2cc1-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C18H17NO3/c1-19(2)14-7-4-12(5-8-14)15-10-13-6-9-18(20)22-16(13)11-17(15)21-3/h4-11H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.34E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50355216
PNG
(CHEMBL1835807)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccccc1
Show InChI InChI=1S/C19H19NO2/c1-3-20(4-2)17-13-18-15(10-11-19(21)22-18)12-16(17)14-8-6-5-7-9-14/h5-13H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.54E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Displacement of [3H]-dexamethasone from human recombinant glucocorticoid receptor after 18 hrs by liquid scintillation counting

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355215
PNG
(CHEMBL1835806)
Show SMILES CCOC(=O)c1cc2cc(-c3ccccc3)c(cc2oc1=O)N(CC)CC
Show InChI InChI=1S/C22H23NO4/c1-4-23(5-2)19-14-20-16(12-17(19)15-10-8-7-9-11-15)13-18(22(25)27-20)21(24)26-6-3/h7-14H,4-6H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.07E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50355239
PNG
(CHEMBL1835832)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1cccs1
Show InChI InChI=1S/C17H17NO2S/c1-3-18(4-2)14-11-15-12(7-8-17(19)20-15)10-13(14)16-6-5-9-21-16/h5-11H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.96E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Displacement of [3H]-dexamethasone from human recombinant glucocorticoid receptor after 18 hrs by liquid scintillation counting

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Androgen receptor


(Homo sapiens (Human))		BDBM50355239
PNG
(CHEMBL1835832)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1cccs1
Show InChI InChI=1S/C17H17NO2S/c1-3-18(4-2)14-11-15-12(7-8-17(19)20-15)10-13(14)16-6-5-9-21-16/h5-11H,3-4H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.70E+3n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Displacement of [3H]DHT from human recombinant androgen receptor-LBD expressed in Escherichia coli after 18 hrs by liquid scintillation counting

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355240
PNG
(CHEMBL1835833)
Show SMILES O=c1ccc2cc(ccc2o1)-c1cccs1
Show InChI InChI=1S/C13H8O2S/c14-13-6-4-9-8-10(3-5-11(9)15-13)12-2-1-7-16-12/h1-8H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Displacement of [1,2,6,7-3H]PG from human PR-LBD after 24 hrs by liquid scintillation counting

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Androgen receptor


(Homo sapiens (Human))		BDBM50355216
PNG
(CHEMBL1835807)
Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccccc1
Show InChI InChI=1S/C19H19NO2/c1-3-20(4-2)17-13-18-15(10-11-19(21)22-18)12-16(17)14-8-6-5-7-9-14/h5-13H,3-4H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Displacement of [3H]DHT from human recombinant androgen receptor-LBD expressed in Escherichia coli after 18 hrs by liquid scintillation counting

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355243
PNG
(CHEMBL1835836)
Show SMILES Cn1c(ccc1-c1ccc2oc(=O)ccc2c1)C#N
Show InChI InChI=1S/C15H10N2O2/c1-17-12(9-16)4-5-13(17)10-2-6-14-11(8-10)3-7-15(18)19-14/h2-8H,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.52E+4n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Displacement of [1,2,6,7-3H]PG from human PR-LBD after 24 hrs by liquid scintillation counting

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355238
PNG
(CHEMBL1835831)
Show SMILES O=c1ccc2cc(ccc2o1)-c1cccc(c1)-c1cccnc1
Show InChI InChI=1S/C20H13NO2/c22-20-9-7-17-12-16(6-8-19(17)23-20)14-3-1-4-15(11-14)18-5-2-10-21-13-18/h1-13H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.79E+4n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))		BDBM50355241
PNG
(CHEMBL1835834)
Show SMILES Clc1ccc(s1)-c1ccc2oc(=O)ccc2c1
Show InChI InChI=1S/C13H7ClO2S/c14-12-5-4-11(17-12)9-1-3-10-8(7-9)2-6-13(15)16-10/h1-7H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.05E+4n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Displacement of [1,2,6,7-3H]PG from human PR-LBD after 24 hrs by liquid scintillation counting

J Med Chem 54: 7055-65 (2011)


Article DOI: 10.1021/jm2005404
BindingDB Entry DOI: 10.7270/Q27D2VJ6
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%