Affinity Data by PubMed id=21940167

PubMed code 21940167

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50355897 (CHEMBL1910163) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50355899 (CHEMBL1910165) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50355898 (CHEMBL1910164) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50355893 (CHEMBL1910159) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	261	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-MIP-1alpha 125I]-MCP1 from CCR1 expressed in CHO-K1 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50355894 (CHEMBL1910160) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	387	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-MIP-1alpha 125I]-MCP1 from CCR1 expressed in CHO-K1 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50355895 (CHEMBL1910161) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	925	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-MIP-1alpha 125I]-MCP1 from CCR2 expressed in CHO ducX#98 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50355895 (CHEMBL1910161) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50355901 (CHEMBL1910166) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-MIP-1- alpha from CCR5 expressed in CHO K1 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50355900 (CHEMBL1910167) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50355902 (CHEMBL1910168) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-MIP-1- alpha from CCR5 expressed in CHO K1 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50355896 (CHEMBL1910162) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-MIP-1alpha 125I]-MCP1 from CCR2 expressed in CHO ducX#98 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50355900 (CHEMBL1910167) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Displacement of [125I]-MIP-1- alpha from CCR5 expressed in CHO K1 cells by scintillation proximity assay				Bioorg Med Chem Lett 21: 6249-52 (2011) Article DOI: 10.1016/j.bmcl.2011.09.013 BindingDB Entry DOI: 10.7270/Q2XS5VTX
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%