Affinity Data by PubMed id=22014547

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50358566 (UNGEREMINE) Show SMILES [O-]c1cc2CC[n+]3cc4cc5OCOc5cc4c(c1)c23 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 1-mediated relaxation of supercoiled pBR322 DNA				Bioorg Med Chem Lett 21: 7041-4 (2011) Article DOI: 10.1016/j.bmcl.2011.09.097 BindingDB Entry DOI: 10.7270/Q2B858K9
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50358566 (UNGEREMINE) Show SMILES [O-]c1cc2CC[n+]3cc4cc5OCOc5cc4c(c1)c23 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 DNA				Bioorg Med Chem Lett 21: 7041-4 (2011) Article DOI: 10.1016/j.bmcl.2011.09.097 BindingDB Entry DOI: 10.7270/Q2B858K9
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%