Affinity Data by PubMed id=22071524

PubMed code 22071524

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione \| 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O \|t:1\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAO-B expressed in baculovirus infected insect cells using benzylamine as substrate by Lineweaver-Burk pl...				Bioorg Med Chem 19: 7416-24 (2011) Article DOI: 10.1016/j.bmc.2011.10.049 BindingDB Entry DOI: 10.7270/Q2571CFB
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50013811 (9H-beta-Carboline \| 9H-pyrido[3,4-b]indole \| CHEMB...) Show SMILES c1ccc2c(c1)[nH]c1cnccc21 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Reversible inhibition of MAO-B				Bioorg Med Chem 19: 7416-24 (2011) Article DOI: 10.1016/j.bmc.2011.10.049 BindingDB Entry DOI: 10.7270/Q2571CFB
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM24776 (1,4-Naphthoquinone \| 1,4-Naphthoquinone (5a) \| 1,4...) Show SMILES O=C1C=CC(=O)c2ccccc12 \|c:2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAO-B expressed in baculovirus infected insect cells using benzylamine as substrate by Lineweaver-Burk pl...				Bioorg Med Chem 19: 7416-24 (2011) Article DOI: 10.1016/j.bmc.2011.10.049 BindingDB Entry DOI: 10.7270/Q2571CFB
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50359639 (CHEMBL1928855) Show SMILES CC1=C(C)C(=O)c2cc(C)ccc2C1=O \|c:1\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Competitive inhibition of human MAO-B				Bioorg Med Chem 19: 7416-24 (2011) Article DOI: 10.1016/j.bmc.2011.10.049 BindingDB Entry DOI: 10.7270/Q2571CFB
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50359639 (CHEMBL1928855) Show SMILES CC1=C(C)C(=O)c2cc(C)ccc2C1=O \|c:1\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Competitive inhibition of human MAO-A				Bioorg Med Chem 19: 7416-24 (2011) Article DOI: 10.1016/j.bmc.2011.10.049 BindingDB Entry DOI: 10.7270/Q2571CFB
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM24776 (1,4-Naphthoquinone \| 1,4-Naphthoquinone (5a) \| 1,4...) Show SMILES O=C1C=CC(=O)c2ccccc12 \|c:2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Noncompetitive inhibition of human recombinant MAO-A expressed in baculovirus infected insect cells using p-tyramine as substrate by Lineweaver-Burk ...				Bioorg Med Chem 19: 7416-24 (2011) Article DOI: 10.1016/j.bmc.2011.10.049 BindingDB Entry DOI: 10.7270/Q2571CFB
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione \| 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O \|t:1\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAO-A expressed in baculovirus infected insect cells using p-tyramine as substrate by Lineweaver-Burk plo...				Bioorg Med Chem 19: 7416-24 (2011) Article DOI: 10.1016/j.bmc.2011.10.049 BindingDB Entry DOI: 10.7270/Q2571CFB
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%