Affinity Data by PubMed id=22100137

PubMed code 22100137

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50292429 (2-Hydroxy-6-pentadecyl-benzoic acid \| 2-Pentadecyl...) Show SMILES OC(=O)c1c(O)cccc1CCCCCCC\C=C/C\C=C/CC=C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged p300 HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrat...				Eur J Med Chem 47: 337-44 (2012) Article DOI: 10.1016/j.ejmech.2011.11.001 BindingDB Entry DOI: 10.7270/Q2XD123P
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50292429 (2-Hydroxy-6-pentadecyl-benzoic acid \| 2-Pentadecyl...) Show SMILES OC(=O)c1c(O)cccc1CCCCCCC\C=C/C\C=C/CC=C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged PCAF HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrat...				Eur J Med Chem 47: 337-44 (2012) Article DOI: 10.1016/j.ejmech.2011.11.001 BindingDB Entry DOI: 10.7270/Q2XD123P
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM50292429 (2-Hydroxy-6-pentadecyl-benzoic acid \| 2-Pentadecyl...) Show SMILES OC(=O)c1c(O)cccc1CCCCCCC\C=C/C\C=C/CC=C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human MOF expressed in Escherichia coli BL21(DE3) cells using [14C]AC-CoA and histone H4 as substrate after 5 mins by scintillation cou...				Eur J Med Chem 47: 337-44 (2012) Article DOI: 10.1016/j.ejmech.2011.11.001 BindingDB Entry DOI: 10.7270/Q2XD123P
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM50360449 (CHEMBL1215739 \| MG-149) Show SMILES CCCCCCCc1ccc(CCc2cccc(O)c2C(O)=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human MOF expressed in Escherichia coli BL21(DE3) cells using [14C]AC-CoA and histone H4 as substrate after 5 mins by scintillation cou...				Eur J Med Chem 47: 337-44 (2012) Article DOI: 10.1016/j.ejmech.2011.11.001 BindingDB Entry DOI: 10.7270/Q2XD123P
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT5 (Homo sapiens (Human))	BDBM50292429 (2-Hydroxy-6-pentadecyl-benzoic acid \| 2-Pentadecyl...) Show SMILES OC(=O)c1c(O)cccc1CCCCCCC\C=C/C\C=C/CC=C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged Tip60 expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate after 5 ...				Eur J Med Chem 47: 337-44 (2012) Article DOI: 10.1016/j.ejmech.2011.11.001 BindingDB Entry DOI: 10.7270/Q2XD123P
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT5 (Homo sapiens (Human))	BDBM50360449 (CHEMBL1215739 \| MG-149) Show SMILES CCCCCCCc1ccc(CCc2cccc(O)c2C(O)=O)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged Tip60 expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate after 5 ...				Eur J Med Chem 47: 337-44 (2012) Article DOI: 10.1016/j.ejmech.2011.11.001 BindingDB Entry DOI: 10.7270/Q2XD123P
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%