Affinity Data by PubMed id=22113110

PubMed code 22113110

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D-alanyl-D-alanine dipeptidase (Enterococcus faecium)	BDBM50361935 (CHEMBL1939351) Show SMILES C[C@H](N)P(O)(=O)OCC(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea...				Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F
Northwest University Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine dipeptidase (Enterococcus faecium)	BDBM50361940 (CHEMBL1939352) Show SMILES C[C@H](N)P(O)(=O)O[C@H](C)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Competitive inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated fo...				Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F
Northwest University Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine dipeptidase (Enterococcus faecium)	BDBM50361937 (CHEMBL1939354) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+6	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea...				Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F
Northwest University Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine dipeptidase (Enterococcus faecium)	BDBM50361938 (CHEMBL1939355) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+6	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea...				Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F
Northwest University Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine dipeptidase (Enterococcus faecium)	BDBM50361936 (CHEMBL1939353) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+6	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea...				Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F
Northwest University Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine dipeptidase (Enterococcus faecium)	BDBM50361939 (CHEMBL1939356) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.21E+6	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea...				Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F
Northwest University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%