Affinity Data by PubMed id=22154664

PubMed code 22154664

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50361151 (CHEMBL1933805) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay				Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W
The Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50361149 (CHEMBL1933803) Show SMILES COc1ccc2c(Cl)c(sc2c1)C(=O)N(C)Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay				Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W
The Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50070942 ((-)-Epigallocatechin gallate \| (-)-Epigallocatechi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay				Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W
The Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50361150 (CHEMBL1933804) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay				Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W
The Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50361152 (CHEMBL1933806) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay				Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W
The Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50361148 (CHEMBL1933802) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay				Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W
The Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50361147 (CHEMBL1933801) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay				Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W
The Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%