Affinity Data by PubMed id=22225576

PubMed code 22225576

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50307794 (2-(4-isobutylphenyl)-N-(3-methylpyridin-2-yl)propa...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)Nc1ncccc1C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50307794 (2-(4-isobutylphenyl)-N-(3-methylpyridin-2-yl)propa...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)Nc1ncccc1C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM237307 (4-Acetamidophenyl 2-(2-(4-isobutylphenyl)propanami...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM237308 (ibu-am14 (9)) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM237310 (2-(4-Isobutylphenyl)-N-(3-(3-methylpyridin-2-ylami...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM237312 (2-(4-Isobutylphenyl)-N-(2-oxo-2-(pyridin-3-ylmethy...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM237311 (2-(4-Isobutylphenyl)-N-(2-oxo-2-(pyridin-2- ylmeth...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM237306 (3-Methylpyridin-2-yl 2-(4-isobutylphenyl)propanoat...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)Oc1ncccc1C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+5	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50009859 ((+-)-2-(p-isobutylphenyl)propionic acid \| (+-)-alp...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.34E+5	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM237309 (2-(4-Isobutylphenyl)-N-(2-(6-methylpyridin-2-ylami...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50009859 ((+-)-2-(p-isobutylphenyl)propionic acid \| (+-)-alp...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.63E+5	n/a	n/a	n/a	n/a	7.0	4
Ume� University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
Ume� University					More data for this Ligand-Target Pair

* indicates data uncertainty>20%