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PubMed code 22429467

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))
BDBM50340226
PNG
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-(oxazol...)
Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)-c2ncco2)cn1
Show InChI InChI=1S/C16H14N6O2/c1-9-2-3-10(7-19-9)8-22-12-6-11(15-18-4-5-24-15)20-14(17)13(12)21-16(22)23/h2-7H,8H2,1H3,(H2,17,20)(H,21,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 100n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Agonist activity at TLR7


Bioorg Med Chem Lett 22: 2856-60 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.069
BindingDB Entry DOI: 10.7270/Q2KH0PC8
More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM50340220
PNG
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-(triflu...)
Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)cn1
Show InChI InChI=1S/C14H12F3N5O/c1-7-2-3-8(5-19-7)6-22-9-4-10(14(15,16)17)20-12(18)11(9)21-13(22)23/h2-5H,6H2,1H3,(H2,18,20)(H,21,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 50n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Agonist activity at TLR7


Bioorg Med Chem Lett 22: 2856-60 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.069
BindingDB Entry DOI: 10.7270/Q2KH0PC8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%