Affinity Data by PubMed id=22578460

PubMed code 22578460

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
14-3-3 protein gamma (Homo sapiens (Human))	BDBM50383920 (CHEMBL2031675) Show SMILES Oc1ccc(CCOC(=O)Cc2ccc(O)c(O)c2)cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged 14-3-3gamma interaction with TMR-pS259-Raf peptide after 30 mins by fluorescence polarization assay				Bioorg Med Chem Lett 22: 4179-81 (2012) Article DOI: 10.1016/j.bmcl.2012.04.027 BindingDB Entry DOI: 10.7270/Q2ZC83W1
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
14-3-3 protein gamma (Homo sapiens (Human))	BDBM50383921 (CHEMBL2031676) Show SMILES Oc1ccc(cc1O)C1OCCc2cc(O)c(O)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged 14-3-3gamma interaction with TMR-pS259-Raf peptide after 30 mins by fluorescence polarization assay				Bioorg Med Chem Lett 22: 4179-81 (2012) Article DOI: 10.1016/j.bmcl.2012.04.027 BindingDB Entry DOI: 10.7270/Q2ZC83W1
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
14-3-3 protein gamma (Homo sapiens (Human))	BDBM50383920 (CHEMBL2031675) Show SMILES Oc1ccc(CCOC(=O)Cc2ccc(O)c(O)c2)cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged 14-3-3gamma interaction with PRAS40 in Cos7 cell lysate by ELISA				Bioorg Med Chem Lett 22: 4179-81 (2012) Article DOI: 10.1016/j.bmcl.2012.04.027 BindingDB Entry DOI: 10.7270/Q2ZC83W1
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
14-3-3 protein gamma (Homo sapiens (Human))	BDBM50383921 (CHEMBL2031676) Show SMILES Oc1ccc(cc1O)C1OCCc2cc(O)c(O)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged 14-3-3gamma interaction with PRAS40 in Cos7 cell lysate by ELISA				Bioorg Med Chem Lett 22: 4179-81 (2012) Article DOI: 10.1016/j.bmcl.2012.04.027 BindingDB Entry DOI: 10.7270/Q2ZC83W1
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%