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PubMed code 22659092

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
UDP-glucuronosyltransferase 1A9


(Homo sapiens (Human))
BDBM50008347
PNG
(5-(2-(diethylamino)ethylamino)-8-hydroxy-6H-imidaz...)
Show SMILES CCN(CC)CCNc1ccc2ncn3c2c1c(=O)c1cc(O)ccc31
Show InChI InChI=1S/C20H22N4O2/c1-3-23(4-2)10-9-21-15-6-7-16-19-18(15)20(26)14-11-13(25)5-8-17(14)24(19)12-22-16/h5-8,11-12,21,25H,3-4,9-10H2,1-2H3
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Article
PubMed
9.58E+5n/an/an/an/an/an/an/an/a



Gdansk University of Technology

Curated by ChEMBL


Assay Description
Inhibition of human recombinant UGT1A9 activity expressed in baculovirus-infected Sf9 cells


Drug Metab Dispos 40: 1736-43 (2012)


Article DOI: 10.1124/dmd.112.045401
BindingDB Entry DOI: 10.7270/Q25H7J0M
More data for this
Ligand-Target Pair
UDP-glucuronosyltransferase 1A9


(Homo sapiens (Human))
BDBM50088499
PNG
(CHEMBL329092)
Show SMILES CN(C)CCCNc1ccc2nnn3c2c1c(=O)c1cc(O)ccc31
Show InChI InChI=1S/C18H19N5O2/c1-22(2)9-3-8-19-13-5-6-14-17-16(13)18(25)12-10-11(24)4-7-15(12)23(17)21-20-14/h4-7,10,19,24H,3,8-9H2,1-2H3
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antibodypedia
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PC cid
PC sid
UniChem

Similars

Article
PubMed
1.65E+6n/an/an/an/an/an/an/an/a



Gdansk University of Technology

Curated by ChEMBL


Assay Description
Inhibition of human recombinant UGT1A9 activity expressed in baculovirus-infected Sf9 cells


Drug Metab Dispos 40: 1736-43 (2012)


Article DOI: 10.1124/dmd.112.045401
BindingDB Entry DOI: 10.7270/Q25H7J0M
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%