Affinity Data by PubMed id=22662288

PubMed code 22662288

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388903 (CHEMBL2063253) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388906 (CHEMBL2063256) Show SMILES CCCCCCOc1cccc(Cn2ccc(O)c(C(O)=O)c2=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388903 (CHEMBL2063253) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus isolate WT CrtM-mediated staphyloxanthin synthesis after 72 hrs by spectrophotometry				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388903 (CHEMBL2063253) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388904 (CHEMBL2063254) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388906 (CHEMBL2063256) Show SMILES CCCCCCOc1cccc(Cn2ccc(O)c(C(O)=O)c2=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus isolate WT CrtM-mediated staphyloxanthin synthesis after 72 hrs by spectrophotometry				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388906 (CHEMBL2063256) Show SMILES CCCCCCOc1cccc(Cn2ccc(O)c(C(O)=O)c2=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388908 (CHEMBL2063258) Show SMILES CCCCCCCCCCOc1cccc(c1)C(=O)CC(=O)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388909 (CHEMBL2063259) Show SMILES CCCCCCCCOc1ccc(cc1)C(=O)CC(=O)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388905 (CHEMBL2063255) Show SMILES CCCCCCOc1cccc(CCCNC(=O)CC(=O)C(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
4,4'-diapophytoene synthase (Staphylococcus aureus)	BDBM50388907 (CHEMBL2063257) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...				ACS Med Chem Lett 3: 402-406 (2012) Article DOI: 10.1021/ml300038t BindingDB Entry DOI: 10.7270/Q2XW4KVQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)

* indicates data uncertainty>20%