Affinity Data by PubMed id=22748707

PubMed code 22748707

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389272 (CHEMBL2063565) Show SMILES CCCCCc1cn(nn1)C1CCOC1=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as inhibition of 3-oxoC6-HSL-induced q...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
INSA Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389274 (CHEMBL2063588) Show SMILES CCCCCCn1nnnc1C1CCOC1=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as inhibition of 3-oxoC6-HSL-induced q...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
INSA Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389277 (CHEMBL2063591) Show SMILES CCCCCn1nnnc1C1CCOC1=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as inhibition of 3-oxoC6-HSL-induced q...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
INSA Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389273 (CHEMBL2063594) Show SMILES CCCCCc1cn(CC(=O)OCC)nn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as inhibition of 3-oxoC6-HSL-induced q...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
INSA Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389275 (CHEMBL2063589) Show SMILES CCCCCCn1nnnc1CC(=O)OCC Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as inhibition of 3-oxoC6-HSL-induced q...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
INSA Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389276 (CHEMBL2063590) Show SMILES CCCCn1nnnc1C1CCOC1=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as inhibition of 3-oxoC6-HSL-induced q...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
INSA Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389278 (CHEMBL2063592) Show SMILES CCCCCc1nnnn1C1CCOC1=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Agonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as activation of 3-oxoC6-HSL-induced quor...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
INSA Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389279 (CHEMBL2063593) Show SMILES CCCCCCc1nnnn1C1CCOC1=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Agonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as activation of 3-oxoC6-HSL-induced quor...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
INSA Lyon Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%