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PubMed code 22883027

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50485631
PNG
(CHEMBL2088335)
Show SMILES Cc1cc(C)c(c(C)c1)-n1c(SCC(=O)Nc2ccc(cc2Br)S(N)(=O)=O)nc2cnccc12 |(-.67,-53.17,;-1.42,-51.82,;-2.96,-51.79,;-3.7,-50.45,;-5.24,-50.42,;-2.9,-49.13,;-1.37,-49.15,;-.58,-47.83,;-.62,-50.49,;-3.65,-47.78,;-2.75,-46.53,;-1.21,-46.52,;-.45,-45.18,;1.09,-45.17,;1.87,-46.5,;1.85,-43.84,;3.39,-43.83,;4.17,-45.16,;5.71,-45.15,;6.47,-43.81,;5.68,-42.48,;4.15,-42.5,;3.36,-41.17,;8,-43.8,;8.79,-45.13,;8,-42.26,;9.33,-43.02,;-3.67,-45.29,;-5.13,-45.77,;-6.46,-45.01,;-7.79,-45.78,;-7.79,-47.32,;-6.46,-48.1,;-5.12,-47.32,)|
Show InChI InChI=1S/C23H22BrN5O3S2/c1-13-8-14(2)22(15(3)9-13)29-20-6-7-26-11-19(20)28-23(29)33-12-21(30)27-18-5-4-16(10-17(18)24)34(25,31)32/h4-11H,12H2,1-3H3,(H,27,30)(H2,25,31,32)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.40E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of recombinant HIV-1 RT assessed as inhibition of biotin-dUTP incorporation by colorimetric analysis

Bioorg Med Chem 20: 5527-36 (2012)


Article DOI: 10.1016/j.bmc.2012.07.026
BindingDB Entry DOI: 10.7270/Q2QR511G
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%