Affinity Data by PubMed id=22901310

PubMed code 22901310

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50242053 (6,8-didec-(1Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-in...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351144 (CHEMBL1817909 \| CHEMBL2057810) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351145 (CHEMBL1817910 \| CHEMBL2057811) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351149 (CHEMBL1817914 \| CHEMBL2057815) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50387957 (CHEMBL2057813) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50387950 (CHEMBL2057534) Show SMILES CCCCCCCC\C=C/c1c2CCC[n+]2c(C)cc1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50389587 (CHEMBL2064265) Show SMILES CCCCCCCC\C=C\c1c2CCC[n+]2c(C)cc1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351146 (CHEMBL1817911 \| CHEMBL2057814) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50387956 (CHEMBL2057812) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50389588 (CHEMBL2064266) Show SMILES CCCCCCCCCCc1c2CCC[n+]2c(C)cc1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50389585 (CHEMBL2064263) Show SMILES CCCCCCCC\C=C\c1c(C)cc2CCC[n+]2c1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50387951 (CHEMBL2057807) Show SMILES CCCCCCCC\C=C/c1c(C)cc2CCC[n+]2c1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50389586 (CHEMBL2064264) Show SMILES CCCCCCCCCCc1c(C)cc2CCC[n+]2c1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50389582 (CHEMBL2064162) Show SMILES CCCCCCCC\C=C/c1c(C)cc(CCCOC)nc1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50387953 (CHEMBL2057809) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50389584 (CHEMBL2064164) Show SMILES CCCCCCCC\C=C/c1c(C)cc(C)nc1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50389583 (CHEMBL2064163) Show SMILES CCCCCCCC\C=C/c1c(C)cc(C)nc1CCCOC Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50387952 (CHEMBL2057808) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...				Eur J Med Chem 55: 395-408 (2012) Article DOI: 10.1016/j.ejmech.2012.07.049 BindingDB Entry DOI: 10.7270/Q2Q2419S
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%