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PubMed code 23220644

Compile data set for download or QSAR
Found 50 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424427
PNG
(CHEMBL2316064)
Show SMILES COC(=O)NCCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4)cc3)cc12
Show InChI InChI=1S/C26H26N2O5/c1-30-26(29)27-14-13-19-18-28-25-12-11-23(17-24(19)25)32-16-15-31-20-7-9-22(10-8-20)33-21-5-3-2-4-6-21/h2-12,17-18,28H,13-16H2,1H3,(H,27,29)
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n/an/a 670n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM23738
PNG
(2-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)aceta...)
Show SMILES COc1ccc2n(Cc3ccccc3)c(C)c(CC(N)=O)c2c1
Show InChI InChI=1S/C19H20N2O2/c1-13-16(11-19(20)22)17-10-15(23-2)8-9-18(17)21(13)12-14-6-4-3-5-7-14/h3-10H,11-12H2,1-2H3,(H2,20,22)
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n/an/a 880n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424432
PNG
(CHEMBL2316059)
Show SMILES NCCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4)cc3)cc12
Show InChI InChI=1S/C24H24N2O3/c25-13-12-18-17-26-24-11-10-22(16-23(18)24)28-15-14-27-19-6-8-21(9-7-19)29-20-4-2-1-3-5-20/h1-11,16-17,26H,12-15,25H2
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n/an/a 1.30E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424434
PNG
(CHEMBL2316057)
Show SMILES NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12
Show InChI InChI=1S/C23H22N2O/c24-13-12-20-15-25-23-11-10-21(14-22(20)23)26-16-17-6-8-19(9-7-17)18-4-2-1-3-5-18/h1-11,14-15,25H,12-13,16,24H2
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n/an/a 2.10E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424427
PNG
(CHEMBL2316064)
Show SMILES COC(=O)NCCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4)cc3)cc12
Show InChI InChI=1S/C26H26N2O5/c1-30-26(29)27-14-13-19-18-28-25-12-11-23(17-24(19)25)32-16-15-31-20-7-9-22(10-8-20)33-21-5-3-2-4-6-21/h2-12,17-18,28H,13-16H2,1H3,(H,27,29)
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n/an/a 2.40E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424426
PNG
(CHEMBL2316065)
Show SMILES OC(=O)NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12
Show InChI InChI=1S/C24H22N2O3/c27-24(28)25-13-12-20-15-26-23-11-10-21(14-22(20)23)29-16-17-6-8-19(9-7-17)18-4-2-1-3-5-18/h1-11,14-15,25-26H,12-13,16H2,(H,27,28)
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n/an/a 3.80E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a 4.20E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424434
PNG
(CHEMBL2316057)
Show SMILES NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12
Show InChI InChI=1S/C23H22N2O/c24-13-12-20-15-25-23-11-10-21(14-22(20)23)26-16-17-6-8-19(9-7-17)18-4-2-1-3-5-18/h1-11,14-15,25H,12-13,16,24H2
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n/an/a 4.40E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424424
PNG
(CHEMBL2316067)
Show SMILES OC(=O)NCCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4)cc3)cc12
Show InChI InChI=1S/C25H24N2O5/c28-25(29)26-13-12-18-17-27-24-11-10-22(16-23(18)24)31-15-14-30-19-6-8-21(9-7-19)32-20-4-2-1-3-5-20/h1-11,16-17,26-27H,12-15H2,(H,28,29)
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n/an/a 5.20E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424431
PNG
(CHEMBL2316060)
Show SMILES [NH3+]CCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccc(cc4)[N+]([O-])=O)cc3)cc12
Show InChI InChI=1S/C24H23N3O5/c25-12-11-17-16-26-24-10-9-22(15-23(17)24)31-14-13-30-19-5-7-21(8-6-19)32-20-3-1-18(2-4-20)27(28)29/h1-10,15-16,26H,11-14,25H2/p+1
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n/an/a 5.30E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424429
PNG
(CHEMBL2316062)
Show SMILES COC(=O)NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12
Show InChI InChI=1S/C25H24N2O3/c1-29-25(28)26-14-13-21-16-27-24-12-11-22(15-23(21)24)30-17-18-7-9-20(10-8-18)19-5-3-2-4-6-19/h2-12,15-16,27H,13-14,17H2,1H3,(H,26,28)
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n/an/a 5.80E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424430
PNG
(CHEMBL2316061)
Show SMILES [NH3+]CCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4[N+]([O-])=O)cc3)cc12
Show InChI InChI=1S/C24H23N3O5/c25-12-11-17-16-26-22-10-9-20(15-21(17)22)31-14-13-30-18-5-7-19(8-6-18)32-24-4-2-1-3-23(24)27(28)29/h1-10,15-16,26H,11-14,25H2/p+1
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n/an/a 6.80E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424426
PNG
(CHEMBL2316065)
Show SMILES OC(=O)NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12
Show InChI InChI=1S/C24H22N2O3/c27-24(28)25-13-12-20-15-26-23-11-10-21(14-22(20)23)29-16-17-6-8-19(9-7-17)18-4-2-1-3-5-18/h1-11,14-15,25-26H,12-13,16H2,(H,27,28)
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n/an/a 7.08E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424429
PNG
(CHEMBL2316062)
Show SMILES COC(=O)NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12
Show InChI InChI=1S/C25H24N2O3/c1-29-25(28)26-14-13-21-16-27-24-12-11-22(15-23(21)24)30-17-18-7-9-20(10-8-18)19-5-3-2-4-6-19/h2-12,15-16,27H,13-14,17H2,1H3,(H,26,28)
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n/an/a 7.60E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424430
PNG
(CHEMBL2316061)
Show SMILES [NH3+]CCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4[N+]([O-])=O)cc3)cc12
Show InChI InChI=1S/C24H23N3O5/c25-12-11-17-16-26-22-10-9-20(15-21(17)22)31-14-13-30-18-5-7-19(8-6-18)32-24-4-2-1-3-23(24)27(28)29/h1-10,15-16,26H,11-14,25H2/p+1
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n/an/a 8.60E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424436
PNG
(CHEMBL2316069)
Show SMILES NCCc1c[nH]c2ccc(OCc3ccc4ccccc4c3)cc12
Show InChI InChI=1S/C21H20N2O/c22-10-9-18-13-23-21-8-7-19(12-20(18)21)24-14-15-5-6-16-3-1-2-4-17(16)11-15/h1-8,11-13,23H,9-10,14,22H2
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n/an/a 8.70E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424433
PNG
(CHEMBL2316058)
Show SMILES NCCc1c[nH]c2ccc(OCc3cccc(Oc4ccccc4)c3)cc12
Show InChI InChI=1S/C23H22N2O2/c24-12-11-18-15-25-23-10-9-20(14-22(18)23)26-16-17-5-4-8-21(13-17)27-19-6-2-1-3-7-19/h1-10,13-15,25H,11-12,16,24H2
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n/an/a 8.90E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424427
PNG
(CHEMBL2316064)
Show SMILES COC(=O)NCCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4)cc3)cc12
Show InChI InChI=1S/C26H26N2O5/c1-30-26(29)27-14-13-19-18-28-25-12-11-23(17-24(19)25)32-16-15-31-20-7-9-22(10-8-20)33-21-5-3-2-4-6-21/h2-12,17-18,28H,13-16H2,1H3,(H,27,29)
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n/an/a 9.20E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424428
PNG
(CHEMBL2316063)
Show SMILES COC(=O)NCCc1c[nH]c2ccc(OCc3cccc(Oc4ccccc4)c3)cc12
Show InChI InChI=1S/C25H24N2O4/c1-29-25(28)26-13-12-19-16-27-24-11-10-21(15-23(19)24)30-17-18-6-5-9-22(14-18)31-20-7-3-2-4-8-20/h2-11,14-16,27H,12-13,17H2,1H3,(H,26,28)
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n/an/a 9.27E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424425
PNG
(CHEMBL2316066)
Show SMILES OC(=O)NCCc1c[nH]c2ccc(OCc3cccc(Oc4ccccc4)c3)cc12
Show InChI InChI=1S/C24H22N2O4/c27-24(28)25-12-11-18-15-26-23-10-9-20(14-22(18)23)29-16-17-5-4-8-21(13-17)30-19-6-2-1-3-7-19/h1-10,13-15,25-26H,11-12,16H2,(H,27,28)
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n/an/a 9.90E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424432
PNG
(CHEMBL2316059)
Show SMILES NCCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4)cc3)cc12
Show InChI InChI=1S/C24H24N2O3/c25-13-12-18-17-26-24-11-10-22(16-23(18)24)28-15-14-27-19-6-8-21(9-7-19)29-20-4-2-1-3-5-20/h1-11,16-17,26H,12-15,25H2
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n/an/a 1.15E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM82302
PNG
(5-BENZYLOXYTRYPTAMINE | 5-BZT | CAS_20776-45-8 | C...)
Show SMILES NCCc1c[nH]c2ccc(OCc3ccccc3)cc12
Show InChI InChI=1S/C17H18N2O/c18-9-8-14-11-19-17-7-6-15(10-16(14)17)20-12-13-4-2-1-3-5-13/h1-7,10-11,19H,8-9,12,18H2
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n/an/a 1.30E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424432
PNG
(CHEMBL2316059)
Show SMILES NCCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4)cc3)cc12
Show InChI InChI=1S/C24H24N2O3/c25-13-12-18-17-26-24-11-10-22(16-23(18)24)28-15-14-27-19-6-8-21(9-7-19)29-20-4-2-1-3-5-20/h1-11,16-17,26H,12-15,25H2
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n/an/a 1.50E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424433
PNG
(CHEMBL2316058)
Show SMILES NCCc1c[nH]c2ccc(OCc3cccc(Oc4ccccc4)c3)cc12
Show InChI InChI=1S/C23H22N2O2/c24-12-11-18-15-25-23-10-9-20(14-22(18)23)26-16-17-5-4-8-21(13-17)27-19-6-2-1-3-7-19/h1-10,13-15,25H,11-12,16,24H2
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n/an/a 1.53E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424428
PNG
(CHEMBL2316063)
Show SMILES COC(=O)NCCc1c[nH]c2ccc(OCc3cccc(Oc4ccccc4)c3)cc12
Show InChI InChI=1S/C25H24N2O4/c1-29-25(28)26-13-12-19-16-27-24-11-10-21(15-23(19)24)30-17-18-6-5-9-22(14-18)31-20-7-3-2-4-8-20/h2-11,14-16,27H,12-13,17H2,1H3,(H,26,28)
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n/an/a 1.58E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50247033
PNG
(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Show SMILES NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O
Show InChI InChI=1S/C18H18N2O3/c19-16(18(21)22)8-13-10-20-17-7-6-14(9-15(13)17)23-11-12-4-2-1-3-5-12/h1-7,9-10,16,20H,8,11,19H2,(H,21,22)
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n/an/a 1.73E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424434
PNG
(CHEMBL2316057)
Show SMILES NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12
Show InChI InChI=1S/C23H22N2O/c24-13-12-20-15-25-23-11-10-21(14-22(20)23)26-16-17-6-8-19(9-7-17)18-4-2-1-3-5-18/h1-11,14-15,25H,12-13,16,24H2
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n/an/a 1.80E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424428
PNG
(CHEMBL2316063)
Show SMILES COC(=O)NCCc1c[nH]c2ccc(OCc3cccc(Oc4ccccc4)c3)cc12
Show InChI InChI=1S/C25H24N2O4/c1-29-25(28)26-13-12-19-16-27-24-11-10-21(15-23(19)24)30-17-18-6-5-9-22(14-18)31-20-7-3-2-4-8-20/h2-11,14-16,27H,12-13,17H2,1H3,(H,26,28)
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n/an/a 2.50E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424436
PNG
(CHEMBL2316069)
Show SMILES NCCc1c[nH]c2ccc(OCc3ccc4ccccc4c3)cc12
Show InChI InChI=1S/C21H20N2O/c22-10-9-18-13-23-21-8-7-19(12-20(18)21)24-14-15-5-6-16-3-1-2-4-17(16)11-15/h1-8,11-13,23H,9-10,14,22H2
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n/an/a 2.50E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424435
PNG
(CHEMBL2316056)
Show SMILES NCCc1c[nH]c2ccc(OCc3cccc4ccccc34)cc12
Show InChI InChI=1S/C21H20N2O/c22-11-10-16-13-23-21-9-8-18(12-20(16)21)24-14-17-6-3-5-15-4-1-2-7-19(15)17/h1-9,12-13,23H,10-11,14,22H2
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n/an/a 2.70E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424435
PNG
(CHEMBL2316056)
Show SMILES NCCc1c[nH]c2ccc(OCc3cccc4ccccc34)cc12
Show InChI InChI=1S/C21H20N2O/c22-11-10-16-13-23-21-9-8-18(12-20(16)21)24-14-17-6-3-5-15-4-1-2-7-19(15)17/h1-9,12-13,23H,10-11,14,22H2
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n/an/a 3.00E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424429
PNG
(CHEMBL2316062)
Show SMILES COC(=O)NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12
Show InChI InChI=1S/C25H24N2O3/c1-29-25(28)26-14-13-21-16-27-24-12-11-22(15-23(21)24)30-17-18-7-9-20(10-8-18)19-5-3-2-4-6-19/h2-12,15-16,27H,13-14,17H2,1H3,(H,26,28)
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n/an/a 3.80E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424431
PNG
(CHEMBL2316060)
Show SMILES [NH3+]CCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccc(cc4)[N+]([O-])=O)cc3)cc12
Show InChI InChI=1S/C24H23N3O5/c25-12-11-17-16-26-24-10-9-22(15-23(17)24)31-14-13-30-19-5-7-21(8-6-19)32-20-3-1-18(2-4-20)27(28)29/h1-10,15-16,26H,11-14,25H2/p+1
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n/an/a 4.18E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50247033
PNG
(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Show SMILES NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O
Show InChI InChI=1S/C18H18N2O3/c19-16(18(21)22)8-13-10-20-17-7-6-14(9-15(13)17)23-11-12-4-2-1-3-5-12/h1-7,9-10,16,20H,8,11,19H2,(H,21,22)
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n/an/a 4.21E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM82302
PNG
(5-BENZYLOXYTRYPTAMINE | 5-BZT | CAS_20776-45-8 | C...)
Show SMILES NCCc1c[nH]c2ccc(OCc3ccccc3)cc12
Show InChI InChI=1S/C17H18N2O/c18-9-8-14-11-19-17-7-6-15(10-16(14)17)20-12-13-4-2-1-3-5-13/h1-7,10-11,19H,8-9,12,18H2
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n/an/a 5.20E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424426
PNG
(CHEMBL2316065)
Show SMILES OC(=O)NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12
Show InChI InChI=1S/C24H22N2O3/c27-24(28)25-13-12-20-15-26-23-11-10-21(14-22(20)23)29-16-17-6-8-19(9-7-17)18-4-2-1-3-5-18/h1-11,14-15,25-26H,12-13,16H2,(H,27,28)
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n/an/a 5.30E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424425
PNG
(CHEMBL2316066)
Show SMILES OC(=O)NCCc1c[nH]c2ccc(OCc3cccc(Oc4ccccc4)c3)cc12
Show InChI InChI=1S/C24H22N2O4/c27-24(28)25-12-11-18-15-26-23-10-9-20(14-22(18)23)29-16-17-5-4-8-21(13-17)30-19-6-2-1-3-7-19/h1-10,13-15,25-26H,11-12,16H2,(H,27,28)
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n/an/a 5.80E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50424424
PNG
(CHEMBL2316067)
Show SMILES OC(=O)NCCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4)cc3)cc12
Show InChI InChI=1S/C25H24N2O5/c28-25(29)26-13-12-18-17-27-24-11-10-22(16-23(18)24)31-15-14-30-19-6-8-21(9-7-19)32-20-4-2-1-3-5-20/h1-11,16-17,26-27H,12-15H2,(H,28,29)
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n/an/a 7.10E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424435
PNG
(CHEMBL2316056)
Show SMILES NCCc1c[nH]c2ccc(OCc3cccc4ccccc34)cc12
Show InChI InChI=1S/C21H20N2O/c22-11-10-16-13-23-21-9-8-18(12-20(16)21)24-14-17-6-3-5-15-4-1-2-7-19(15)17/h1-9,12-13,23H,10-11,14,22H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424430
PNG
(CHEMBL2316061)
Show SMILES [NH3+]CCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4[N+]([O-])=O)cc3)cc12
Show InChI InChI=1S/C24H23N3O5/c25-12-11-17-16-26-22-10-9-20(15-21(17)22)31-14-13-30-18-5-7-19(8-6-18)32-24-4-2-1-3-23(24)27(28)29/h1-10,15-16,26H,11-14,25H2/p+1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424433
PNG
(CHEMBL2316058)
Show SMILES NCCc1c[nH]c2ccc(OCc3cccc(Oc4ccccc4)c3)cc12
Show InChI InChI=1S/C23H22N2O2/c24-12-11-18-15-25-23-10-9-20(14-22(18)23)26-16-17-5-4-8-21(13-17)27-19-6-2-1-3-7-19/h1-10,13-15,25H,11-12,16,24H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424425
PNG
(CHEMBL2316066)
Show SMILES OC(=O)NCCc1c[nH]c2ccc(OCc3cccc(Oc4ccccc4)c3)cc12
Show InChI InChI=1S/C24H22N2O4/c27-24(28)25-12-11-18-15-26-23-10-9-20(14-22(18)23)29-16-17-5-4-8-21(13-17)30-19-6-2-1-3-7-19/h1-10,13-15,25-26H,11-12,16H2,(H,27,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424436
PNG
(CHEMBL2316069)
Show SMILES NCCc1c[nH]c2ccc(OCc3ccc4ccccc4c3)cc12
Show InChI InChI=1S/C21H20N2O/c22-10-9-18-13-23-21-8-7-19(12-20(18)21)24-14-15-5-6-16-3-1-2-4-17(16)11-15/h1-8,11-13,23H,9-10,14,22H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM23738
PNG
(2-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)aceta...)
Show SMILES COc1ccc2n(Cc3ccccc3)c(C)c(CC(N)=O)c2c1
Show InChI InChI=1S/C19H20N2O2/c1-13-16(11-19(20)22)17-10-15(23-2)8-9-18(17)21(13)12-14-6-4-3-5-7-14/h3-10H,11-12H2,1-2H3,(H2,20,22)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM23738
PNG
(2-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)aceta...)
Show SMILES COc1ccc2n(Cc3ccccc3)c(C)c(CC(N)=O)c2c1
Show InChI InChI=1S/C19H20N2O2/c1-13-16(11-19(20)22)17-10-15(23-2)8-9-18(17)21(13)12-14-6-4-3-5-7-14/h3-10H,11-12H2,1-2H3,(H2,20,22)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424424
PNG
(CHEMBL2316067)
Show SMILES OC(=O)NCCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4)cc3)cc12
Show InChI InChI=1S/C25H24N2O5/c28-25(29)26-13-12-18-17-27-24-11-10-22(16-23(18)24)31-15-14-30-19-6-8-21(9-7-19)32-20-4-2-1-3-5-20/h1-11,16-17,26-27H,12-15H2,(H,28,29)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM82302
PNG
(5-BENZYLOXYTRYPTAMINE | 5-BZT | CAS_20776-45-8 | C...)
Show SMILES NCCc1c[nH]c2ccc(OCc3ccccc3)cc12
Show InChI InChI=1S/C17H18N2O/c18-9-8-14-11-19-17-7-6-15(10-16(14)17)20-12-13-4-2-1-3-5-13/h1-7,10-11,19H,8-9,12,18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50424431
PNG
(CHEMBL2316060)
Show SMILES [NH3+]CCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccc(cc4)[N+]([O-])=O)cc3)cc12
Show InChI InChI=1S/C24H23N3O5/c25-12-11-17-16-26-24-10-9-22(15-23(17)24)31-14-13-30-19-5-7-21(8-6-19)32-20-3-1-18(2-4-20)27(28)29/h1-10,15-16,26H,11-14,25H2/p+1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50247033
PNG
(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Show SMILES NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O
Show InChI InChI=1S/C18H18N2O3/c19-16(18(21)22)8-13-10-20-17-7-6-14(9-15(13)17)23-11-12-4-2-1-3-5-12/h1-7,9-10,16,20H,8,11,19H2,(H,21,22)
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n/an/a 2.31E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...

Eur J Med Chem 59: 160-7 (2013)


Article DOI: 10.1016/j.ejmech.2012.10.057
BindingDB Entry DOI: 10.7270/Q27P90QH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%