Affinity Data by PubMed id=2329571

PubMed code 2329571

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015416 (4,6,7-Trimethyl-2-propyl-benzo[1,3]oxathiol-5-ol \|...) Show SMILES CCCC1Oc2c(S1)c(C)c(O)c(C)c2C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015415 (2-Butyl-4,6,7-trimethyl-benzo[1,3]oxathiol-5-ol \| ...) Show SMILES CCCCC1Oc2c(S1)c(C)c(O)c(C)c2C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015411 (2-Ethyl-4,6,7-trimethyl-benzo[1,3]oxathiol-5-ol \| ...) Show SMILES CCC1Oc2c(S1)c(C)c(O)c(C)c2C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015409 (4,6,7-Trimethyl-2-phenyl-benzo[1,3]oxathiol-5-ol \|...) Show SMILES Cc1c2OC(Sc2c(C)c(O)c1C)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015404 (2-(3-Hydroxy-propyl)-4,6,7-trimethyl-benzo[1,3]oxa...) Show SMILES Cc1c2OC(CCCO)Sc2c(C)c(O)c1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015408 (2,4,6,7-Tetramethyl-benzo[1,3]oxathiol-5-ol \| CHEM...) Show SMILES CC1Oc2c(S1)c(C)c(O)c(C)c2C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015413 (2-Hexyl-4,6,7-trimethyl-benzo[1,3]oxathiol-5-ol \| ...) Show SMILES CCCCCCC1Oc2c(S1)c(C)c(O)c(C)c2C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015410 (2-Heptyl-4,6,7-trimethyl-benzo[1,3]oxathiol-5-ol \|...) Show SMILES CCCCCCCC1Oc2c(S1)c(C)c(O)c(C)c2C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015406 (4,6,7-Trimethyl-benzo[1,3]oxathiol-5-ol \| CHEMBL27...) Show SMILES Cc1c2OCSc2c(C)c(O)c1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50015407 (3-(5-Hydroxy-4,6,7-trimethyl-benzo[1,3]oxathiol-2-...) Show SMILES Cc1c2OC(CCC(N)=O)Sc2c(C)c(O)c1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50008950 (3-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-dihydr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES NC1=NN(CC1)c1cccc(c1)C(F)(F)F \|t:1\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company Ltd. Curated by ChEMBL					Assay Description Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum				J Med Chem 33: 1491-6 (1990) BindingDB Entry DOI: 10.7270/Q2NG4PM6
Sankyo Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%