Found 22 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428970
(CHEMBL2333209)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc2OCOc2c1)C(C)=O |t:9| Show InChI InChI=1S/C19H18N2O4/c1-12(22)21-17(14-5-8-18-19(9-14)25-11-24-18)10-16(20-21)13-3-6-15(23-2)7-4-13/h3-9,17H,10-11H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428969
(CHEMBL1487360)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCOc2c1)c1ccc(C)cc1 |c:4| Show InChI InChI=1S/C19H18N2O3/c1-12-3-5-14(6-4-12)16-10-17(21(20-16)13(2)22)15-7-8-18-19(9-15)24-11-23-18/h3-9,17H,10-11H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50105463
(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)Show SMILES CCn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12 Show InChI InChI=1S/C21H19N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,23H,2,22H2,1H3/p+1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50338860
(1-(5-(Benzo[d][1,3]dioxol-6-yl)-4,5-dihydro-3-phen...)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCOc2c1)c1ccccc1 |c:4| Show InChI InChI=1S/C18H16N2O3/c1-12(21)20-16(10-15(19-20)13-5-3-2-4-6-13)14-7-8-17-18(9-14)23-11-22-17/h2-9,16H,10-11H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50338866
(1-(5-(Benzo[d][1,3]dioxol-6-yl)-3-(4-bromophenyl)-...)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCOc2c1)c1ccc(Br)cc1 |c:4| Show InChI InChI=1S/C18H15BrN2O3/c1-11(22)21-16(13-4-7-17-18(8-13)24-10-23-17)9-15(20-21)12-2-5-14(19)6-3-12/h2-8,16H,9-10H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428968
(CHEMBL2333208)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCOc2c1)c1ccc(Cl)cc1 |c:4| Show InChI InChI=1S/C18H15ClN2O3/c1-11(22)21-16(13-4-7-17-18(8-13)24-10-23-17)9-15(20-21)12-2-5-14(19)6-3-12/h2-8,16H,9-10H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428967
(CHEMBL2333207)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCOc2c1)c1ccc(F)cc1 |c:4| Show InChI InChI=1S/C18H15FN2O3/c1-11(22)21-16(13-4-7-17-18(8-13)24-10-23-17)9-15(20-21)12-2-5-14(19)6-3-12/h2-8,16H,9-10H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428966
(CHEMBL2333210)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCOc2c1)c1ccc(cc1)[N+]([O-])=O |c:4| Show InChI InChI=1S/C18H15N3O5/c1-11(22)20-16(13-4-7-17-18(8-13)26-10-25-17)9-15(19-20)12-2-5-14(6-3-12)21(23)24/h2-8,16H,9-10H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428965
(CHEMBL2333216)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc2OCCOc2c1)C(C)=O |t:9| Show InChI InChI=1S/C20H20N2O4/c1-13(23)22-18(15-5-8-19-20(11-15)26-10-9-25-19)12-17(21-22)14-3-6-16(24-2)7-4-14/h3-8,11,18H,9-10,12H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428964
(CHEMBL2333215)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCOc2c1)c1ccc(C)cc1 |c:4| Show InChI InChI=1S/C20H20N2O3/c1-13-3-5-15(6-4-13)17-12-18(22(21-17)14(2)23)16-7-8-19-20(11-16)25-10-9-24-19/h3-8,11,18H,9-10,12H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428963
(CHEMBL2333211)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCOc2c1)c1ccccc1 |c:4| Show InChI InChI=1S/C19H18N2O3/c1-13(22)21-17(12-16(20-21)14-5-3-2-4-6-14)15-7-8-18-19(11-15)24-10-9-23-18/h2-8,11,17H,9-10,12H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428962
(CHEMBL2333214)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCOc2c1)c1ccc(Br)cc1 |c:4| Show InChI InChI=1S/C19H17BrN2O3/c1-12(23)22-17(11-16(21-22)13-2-5-15(20)6-3-13)14-4-7-18-19(10-14)25-9-8-24-18/h2-7,10,17H,8-9,11H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428961
(CHEMBL2333213)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCOc2c1)c1ccc(Cl)cc1 |c:4| Show InChI InChI=1S/C19H17ClN2O3/c1-12(23)22-17(11-16(21-22)13-2-5-15(20)6-3-13)14-4-7-18-19(10-14)25-9-8-24-18/h2-7,10,17H,8-9,11H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428960
(CHEMBL2333212)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCOc2c1)c1ccc(F)cc1 |c:4| Show InChI InChI=1S/C19H17FN2O3/c1-12(23)22-17(11-16(21-22)13-2-5-15(20)6-3-13)14-4-7-18-19(10-14)25-9-8-24-18/h2-7,10,17H,8-9,11H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428959
(CHEMBL2333217)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCOc2c1)c1ccc(cc1)[N+]([O-])=O |c:4| Show InChI InChI=1S/C19H17N3O5/c1-12(23)21-17(14-4-7-18-19(10-14)27-9-8-26-18)11-16(20-21)13-2-5-15(6-3-13)22(24)25/h2-7,10,17H,8-9,11H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428958
(CHEMBL2333205)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc2OCCCOc2c1)C(C)=O |t:9| Show InChI InChI=1S/C21H22N2O4/c1-14(24)23-19(13-18(22-23)15-4-7-17(25-2)8-5-15)16-6-9-20-21(12-16)27-11-3-10-26-20/h4-9,12,19H,3,10-11,13H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428957
(CHEMBL2333204)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCCOc2c1)c1ccc(C)cc1 |c:4| Show InChI InChI=1S/C21H22N2O3/c1-14-4-6-16(7-5-14)18-13-19(23(22-18)15(2)24)17-8-9-20-21(12-17)26-11-3-10-25-20/h4-9,12,19H,3,10-11,13H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.49E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428956
(CHEMBL2333218)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCCOc2c1)c1ccccc1 |c:4| Show InChI InChI=1S/C20H20N2O3/c1-14(23)22-18(13-17(21-22)15-6-3-2-4-7-15)16-8-9-19-20(12-16)25-11-5-10-24-19/h2-4,6-9,12,18H,5,10-11,13H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428955
(CHEMBL2333203)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCCOc2c1)c1ccc(Br)cc1 |c:4| Show InChI InChI=1S/C20H19BrN2O3/c1-13(24)23-18(12-17(22-23)14-3-6-16(21)7-4-14)15-5-8-19-20(11-15)26-10-2-9-25-19/h3-8,11,18H,2,9-10,12H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428954
(CHEMBL2333202)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCCOc2c1)c1ccc(Cl)cc1 |c:4| Show InChI InChI=1S/C20H19ClN2O3/c1-13(24)23-18(12-17(22-23)14-3-6-16(21)7-4-14)15-5-8-19-20(11-15)26-10-2-9-25-19/h3-8,11,18H,2,9-10,12H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428953
(CHEMBL2333201)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCCOc2c1)c1ccc(F)cc1 |c:4| Show InChI InChI=1S/C20H19FN2O3/c1-13(24)23-18(12-17(22-23)14-3-6-16(21)7-4-14)15-5-8-19-20(11-15)26-10-2-9-25-19/h3-8,11,18H,2,9-10,12H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50428952
(CHEMBL2333206)Show SMILES CC(=O)N1N=C(CC1c1ccc2OCCCOc2c1)c1ccc(cc1)[N+]([O-])=O |c:4| Show InChI InChI=1S/C20H19N3O5/c1-13(24)22-18(15-5-8-19-20(11-15)28-10-2-9-27-19)12-17(21-22)14-3-6-16(7-4-14)23(25)26/h3-8,11,18H,2,9-10,12H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human SGC7901 cells by TRAP assay |
Bioorg Med Chem Lett 23: 1091-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.010
BindingDB Entry DOI: 10.7270/Q2668FJ4 |
More data for this
Ligand-Target Pair | |
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