Affinity Data by PubMed id=23380174

PubMed code 23380174

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram \| 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Limited Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged PDE4B (unknown origin) expressed in Sf9 cells using cAMP as substrate incubated for 15 mins prior to substrate a...				Eur J Med Chem 62: 395-404 (2013) Article DOI: 10.1016/j.ejmech.2012.12.052 BindingDB Entry DOI: 10.7270/Q2VM4DM4
Dr. Reddy's Laboratories Limited Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50429820 (CHEMBL2337706) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Limited Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged PDE4B (unknown origin) expressed in Sf9 cells using cAMP as substrate incubated for 15 mins prior to substrate a...				Eur J Med Chem 62: 395-404 (2013) Article DOI: 10.1016/j.ejmech.2012.12.052 BindingDB Entry DOI: 10.7270/Q2VM4DM4
Dr. Reddy's Laboratories Limited Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%