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PubMed code 23432124

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor 2


(Homo sapiens (Human))
BDBM50427677
PNG
(CHEMBL2323527)
Show SMILES OC(=O)C[C@@]12O[C@H]3C=CCN[C@H]3[C@@H]1C(=O)NC2C(O)=O |r,c:7|
Show InChI InChI=1S/C12H14N2O6/c15-6(16)4-12-7(10(17)14-9(12)11(18)19)8-5(20-12)2-1-3-13-8/h1-2,5,7-9,13H,3-4H2,(H,14,17)(H,15,16)(H,18,19)/t5-,7+,8+,9?,12+/m0/s1
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antibodypedia
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PC sid
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Article
PubMed
5.60E+5n/an/an/an/an/an/an/an/a



Yokohama City University

Curated by ChEMBL


Assay Description
Binding affinity to GluA2 ligand binding domain (unknown origin) by competitive binding assay


J Med Chem 56: 2283-93 (2013)


Article DOI: 10.1021/jm301590z
BindingDB Entry DOI: 10.7270/Q2SJ1MZN
More data for this
Ligand-Target Pair
Glutamate receptor 2


(Rattus norvegicus)
BDBM50178141
PNG
((S)-1-(2-amino-2-carboxyethyl)-3-(4-carboxybenzyl)...)
Show SMILES N[C@@H](Cn1ccc(=O)n(Cc2ccc(cc2)C(O)=O)c1=O)C(O)=O
Show InChI InChI=1S/C15H15N3O6/c16-11(14(22)23)8-17-6-5-12(19)18(15(17)24)7-9-1-3-10(4-2-9)13(20)21/h1-6,11H,7-8,16H2,(H,20,21)(H,22,23)/t11-/m0/s1
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Similars

MMDB
PDB
Article
PubMed
n/an/a 2.90E+5n/an/an/an/an/an/a



Yokohama City University

Curated by ChEMBL


Assay Description
Displacement of [3H]AMPA from rat GluA2 ligand binding domain after 1 hr


J Med Chem 56: 2283-93 (2013)


Article DOI: 10.1021/jm301590z
BindingDB Entry DOI: 10.7270/Q2SJ1MZN
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
* indicates data uncertainty>20%