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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Histone deacetylase 3 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 28.4 | n/a | n/a | n/a | n/a | n/a | 37 |
Shandong University | Assay Description Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ... | Chem Biol Drug Des 82: 125-30 (2013) Article DOI: 10.1111/cbdd.12144 BindingDB Entry DOI: 10.7270/Q27W69VZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM106369 (ZYJ-34v (Compound 2)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 37.6 | n/a | n/a | n/a | n/a | n/a | 37 |
Shandong University | Assay Description Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ... | Chem Biol Drug Des 82: 125-30 (2013) Article DOI: 10.1111/cbdd.12144 BindingDB Entry DOI: 10.7270/Q27W69VZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 75.6 | n/a | n/a | n/a | n/a | n/a | 37 |
Shandong University | Assay Description Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ... | Chem Biol Drug Des 82: 125-30 (2013) Article DOI: 10.1111/cbdd.12144 BindingDB Entry DOI: 10.7270/Q27W69VZ | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Histone deacetylase 3 (Homo sapiens (Human)) | BDBM106369 (ZYJ-34v (Compound 2)) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 87.7 | n/a | n/a | n/a | n/a | n/a | 37 |
Shandong University | Assay Description Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ... | Chem Biol Drug Des 82: 125-30 (2013) Article DOI: 10.1111/cbdd.12144 BindingDB Entry DOI: 10.7270/Q27W69VZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 6 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | 37 |
Shandong University | Assay Description Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ... | Chem Biol Drug Des 82: 125-30 (2013) Article DOI: 10.1111/cbdd.12144 BindingDB Entry DOI: 10.7270/Q27W69VZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM106369 (ZYJ-34v (Compound 2)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 175 | n/a | n/a | n/a | n/a | n/a | 37 |
Shandong University | Assay Description Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ... | Chem Biol Drug Des 82: 125-30 (2013) Article DOI: 10.1111/cbdd.12144 BindingDB Entry DOI: 10.7270/Q27W69VZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 256 | n/a | n/a | n/a | n/a | n/a | 37 |
Shandong University | Assay Description Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ... | Chem Biol Drug Des 82: 125-30 (2013) Article DOI: 10.1111/cbdd.12144 BindingDB Entry DOI: 10.7270/Q27W69VZ | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Histone deacetylase 6 (Homo sapiens (Human)) | BDBM106369 (ZYJ-34v (Compound 2)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 675 | n/a | n/a | n/a | n/a | n/a | 37 |
Shandong University | Assay Description Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ... | Chem Biol Drug Des 82: 125-30 (2013) Article DOI: 10.1111/cbdd.12144 BindingDB Entry DOI: 10.7270/Q27W69VZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
