Affinity Data by PubMed id=23597047

PubMed code 23597047

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50420419 (CHEMBL2089337) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Partial agonist activity at human A3 adenosine receptor				J Med Chem 56: 3749-67 (2013) Article DOI: 10.1021/jm400422s BindingDB Entry DOI: 10.7270/Q2N58NR0
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50420427 (CHEMBL2089346) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Antagonist activity at A3 adenosine receptor (unknown origin) assessed as inhibition of adenylate cyclase activity				J Med Chem 56: 3749-67 (2013) Article DOI: 10.1021/jm400422s BindingDB Entry DOI: 10.7270/Q2N58NR0
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50432633 (CHEMBL2347371) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor transfected in CHO cells after 60 mins by liquid scintillation counting ...				J Med Chem 56: 3749-67 (2013) Article DOI: 10.1021/jm400422s BindingDB Entry DOI: 10.7270/Q2N58NR0
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50432634 (CHEMBL2347374) Show SMILES CCOc1cccc2cc(C(=O)NCc3ccccn3)c(=N)oc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human recombinant A1 adenosine receptor transfected in CHO cells after 60 mins by liquid scintillation counting analys...				J Med Chem 56: 3749-67 (2013) Article DOI: 10.1021/jm400422s BindingDB Entry DOI: 10.7270/Q2N58NR0
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50432634 (CHEMBL2347374) Show SMILES CCOc1cccc2cc(C(=O)NCc3ccccn3)c(=N)oc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]CGS21680 from human A2A adenosine receptor transfected in HEK293 cells after 60 mins by liquid scintillation counting analysis				J Med Chem 56: 3749-67 (2013) Article DOI: 10.1021/jm400422s BindingDB Entry DOI: 10.7270/Q2N58NR0
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%